A simple pathway for the fabrication of real moth eyelike patterned (MEP) polymer film with a double-layered nano/microhierarchical structure is demonstrated through a solid/liquid interfacial reaction at atmospheric conditions. A convex-structured polyvinyl alcohol (PVA) film containing CdCl 2 was first fabricated using a self-organized honeycomb-patterned porous film as a template. The CdCl 2 /PVA convex film was immersed into Na 2 S/ethanol solution to facilitate the reaction between CdCl 2 and Na 2 S at the solid/liquid interface, which led to the functionalization of CdS nanoparticles in the convex-structured PVA film. The tunable introduction of interfacial reaction resulted in the formation of a CdS moth eyelike nanoarray on the top surface of the PVA convex microarray, which mimicked the real moth eye (PVA−CdS MEP). PVA−CdS MEP film with a double moth eyelike structure showed improved antireflective property in comparison with flat and convex-structured PVA films. The PVA−CdS MEP film showed photoresponse under simulated solar light radiation and flexible duration after 500 cycles of folding.