The state of the future is solid

Cadmium-zinc-telluride myocardial perfusion imaging: The dream of a single test gets nearer

“…7 The recent introduction of the cadmium-zinc-telluride (CZT) cameras for SPECT has purportedly revolutionized MPI, thanks to their superior spatial and energy resolution. 8,9 Given their groundbreaking technical features and the differences between the two available but competing suites (D-SPECT, Spectrum Dynamics, Palo Alto, CA, USA; Discovery NM 530c or Discovery NM/CT 570c with Alcyone technology, GE Healthcare, Haifa, Israel), there are, however, ongoing developments and refinements in the application of this imaging technology to current cardiovascular practice. [10][11][12] Accordingly, the scholarly literature on CZT MPI is continuing to expand momentously, as demonstrated by the work by Jameria and colleagues published in this issue of the Journal.…”

“…In light of the work of Jameria and colleagues, and the total body of evidence on this topic, [8][9][10][11][12] it is important to highlight the current and future prospects of CZT technology for MPI. First, it is paramount to recognize that the two available embodiments of this technology (Alcyone and D-SPECT) might not be identical in performance, despite aggregate analyses suggesting the contrary.…”

“…12,14,15 Second, irrespective of the chosen CZT technology, the spatial and energy resolution of these cameras is significantly superior to that of Anger cameras. 8 These technical advantages might translate into improvements in sensitivity and specificity, after an adequate learning curve, on top of providing some practical perks in testing procedures, such as stress-only protocol for radiation exposure reduction and dual-isotope imaging when a single acquisition is appropriate. 10,11 Exploitation of the superior sensitivity of CZT technology means that we can reduce acquisition time if radionuclide doses similar to those used with Anger cameras are chosen, but, much more importantly, that doses can be dramatically reduced if acquisition times are only moderately decreased.…”

Design and development of the DE-SPECT system: a clinical SPECT system for broadband multi-isotope imaging of peripheral vascular disease

“…Whereas several SPECT radiotracers are readily available in clinics for PVD applications (Stacy et al 2013 , Chou and Stacy 2020 ), the success of multi-tracer SPECT imaging has been limited due to the relatively poor energy resolution of current clinical SPECT instrumentation based on traditional scintillator detectors (Sharir et al 2010 , Karimeddini and Bergmann 2016 ). No organ-dedicated or tailored imaging systems for nuclear medicine applications is currently available to image lower extremities.…”

Scintillation cameras: A new clinical era has come

“…There is no doubt that we are entering into a new clinical era where it is likely that conventional NaI crystal SPECT cameras will be progressively but irremediably replaced by CZT SPECT/CT cameras, giving the field on nuclear cardiology access to a wide variety of imaging protocols which can be tailored to the specific clinical needs. As appropriately stated by Karimeddini and Bergmann in their editorial published in 2015 16 on the new SPECT cameras using solid-state CZT detectors, ''the future of nuclear cardiology is solid (state) and bright''.…”