The Structure and Estimation of Natural Products Functionally Related to Nicotinic Acid.

Heat capacity and thermodynamics of solid and liquid pyridine-3-carboxylic acid (nicotinic acid) over the temperature range 296K to 531K

“…Also shown in table 3 are the analogous values for C(graphite), H 2 (g), N 2 (g), and O 2 (g) used in the calculation of the D f G o m vs T phase diagram of nicotinic acid described in section 3.3. These were obtained by fitting equation (6) to data retrieved from the JANAF tables [49].…”

“…It has for example been used in matrices for matrixassisted laser desorption ionization (MALDI) mass spectrometry analyses of large polypeptides [1], as a reference material for combustion calorimetry [2,3], and particularly as an active pharmaceutical ingredient (API) in the treatment of hypercholesterolemia and atherosclerosis [4,5]. It has also long been recognized as a watersoluble vitamin (vitamin B 3 or niacin) [6,7] indispensable in the diet of humans and animals and, as such, widely used as additive in food, forage, and cosmetics [8,9]. Some recent estimates of the world demand for compounds of the nicotinic acid family point to 35,000 t to 40,000 t [10][11][12].…”

The utilization of nicotinamide derivatives and related compounds by mammals, insects and bacteria

“…The utilization of a number of compounds related to nicotinic acid by various bacteria (Staphylococcus aureus, Proteus vulgaris, dysentery bacilli, Lactobaciltus arabinosus) has been studied by Landy (1938), Fildes (1938), Lwoff (1938), Lwoff & Querido (1939), Dorfman, Koser, Reames, Swingle & Saunders (1939), Pelczar & Porter (1940), Elvehjem & Teply (1943) and v. Euler, H6gberg, Karrer, Salomon & Ruckstuhl (1944). Of the compounds tested, nicotinic acid, nicotinamide, methyl, ethyl, propyl and butyl nicotinate, and nicotinuric acid could be utilized by all bacteria examined, nicotinethylamide and -diethylamide and quinolinic acid were reported to be utilized by Proteus and dysentery bacilli.…”

Solution thermodynamics of aqueous nicotinic acid solutions in presence of tetrabutylammonium hydrogen sulphate

“…1 This is because of its versatility in terms of chemical, biochemical and therapeutic applications. 1 This is because of its versatility in terms of chemical, biochemical and therapeutic applications.…”