Blue straggler stars (BSSs) in globular clusters (GCs) are commonly defined as those stars located along an extrapolation of the main sequence (MS), in a region brighter and bluer (hotter) than the turnoff (TO) point, in the optical colourmagnitude diagram (CMD; see Fig. 5.1). They were first discovered by Sandage [70] in the external region of the Galactic GC M3. Their origin has been a mystery for many years and the puzzle of their formation is not completely solved yet.The BSS location in the CMD suggests that they are more massive than the current cluster population ( Fig. 5.1; this is also confirmed by a few mass measurements, e.g., [74,35]). However, GCs are completely devoid of gas and any recent star formation event can be realistically ruled out. Hence the BSS origin should be searched in some mechanisms able to increase the initial mass of single stars in a sort of rejuvenation process. The BSS formation mechanisms are not completely understood yet, but the main leading scenarios, at present, are mass transfer (MT) processes between binary companions [58,82], possibly up to the complete coalescence of the binary system, or the merger of stars induced by collisions (COLL; [37]). Being more massive than the average cluster stars, BSSs suffer from the effect of dynamical friction, that makes them sink towards the cluster centre [53,32]. In turn, the frequent stellar interactions occurring in the ultra-dense cores of Galactic GCs can promote both the formation and the hardening of binary systems, thus contributing to generate MT-BSSs. All these considerations clearly show that BSSs represent a crucial link between standard stellar evolution and GC internal dynamics (see [3,32], and references therein).