The study of air-plasma treatment on corn starch/poly(ε-caprolactone) films

Arolkar, Gauree A.; Salgo, M.J.; Kelkar-Mane, Varsha; Deshmukh, Rajendra R.

doi:10.1016/j.polymdegradstab.2015.07.016

Cited by 43 publications

(21 citation statements)

References 37 publications

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“…In addition, plasma surface treatment does not use additional chemicals, and thus does not require additional steps such as washing; it also avoids the cytotoxic effect resulting from residual hazardous chemicals. Plasma treatment is widely used in biomedical applications because it can be modified to surfaces with different properties that arise from the chemical structure of the monomer of the polymer [ 24 , 25 ]. The technique exhibits high efficiency on 2D substrates; however, it has considerable limitations in 3D scaffolds because it cannot treat the internal region [ 26 ].…”

Section: Introductionmentioning

confidence: 99%

3D-Printed Poly(ε-Caprolactone)/Hydroxyapatite Scaffolds Modified with Alkaline Hydrolysis Enhance Osteogenesis In Vitro

et al. 2021

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The 3D-printed bioactive ceramic incorporated Poly(ε-caprolactone) (PCL) scaffolds show great promise as synthetic bone graft substitutes. However, 3D-printed scaffolds still lack adequate surface properties for cells to be attached to them. In this study, we modified the surface characteristics of 3D-printed poly(ε-caprolactone)/hydroxyapatite scaffolds using O2 plasma and sodium hydroxide. The surface property of the alkaline hydrolyzed and O2 plasma-treated PCL/HA scaffolds were evaluated using field-emission scanning microscopy (FE-SEM), Alizarin Red S (ARS) staining, and water contact angle analysis, respectively. The in vitro behavior of the scaffolds was investigated using human dental pulp-derived stem cells (hDPSCs). Cell proliferation of hDPSCs on the scaffolds was evaluated via immunocytochemistry (ICC) and water-soluble tetrazolium salt (WST-1) assay. Osteogenic differentiation of hDPSCs on the scaffolds was further investigated using ARS staining and Western blot analysis. The result of this study shows that alkaline treatment is beneficial for exposing hydroxyapatite particles embedded in the scaffolds compared to O2 plasma treatment, which promotes cell proliferation and differentiation of hDPSCs.

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Section: Introductionmentioning

confidence: 99%

3D-Printed Poly(ε-Caprolactone)/Hydroxyapatite Scaffolds Modified with Alkaline Hydrolysis Enhance Osteogenesis In Vitro

et al. 2021

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“…Furthermore, high‐resolution XPS C1s core‐level spectra indicated increases in intensities of C2 (CO, CN) and C3 (CO) peaks. These results indicated that oxygen and nitrogen were introduced as CO, CN, or CO bonds during the plasma treatment, which will enhance the interfacial interactions with the polyelectrolytes in LbL films . PAMAM was chosen as the LbL assembly building blocks because of its ability to hold a variety of molecules, which in turn serve as effective molecular reservoirs.…”

Section: Resultsmentioning

confidence: 99%

A New Way to Promote Molecular Drug Release during Medical Treatment: A Polyelectrolyte Matrix on a Piezoelectric–Dielectric Energy Conversion Substrate

Zhang

Tong

et al. 2018

Small

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Enhanced drug releases in a timely manner during urgent medical treatments would significantly enhance the prognosis of patients. Inspired by the facilitated molecular transports by the potentials, an enhanced drug release strategy driven by mechanical disturbances that widely exist in medical treatment processes is proposed. This strategy is enabled by a functional material comprised of multilayers of dendrimers as the drug reservoir, which are built on a piezoelectric-dielectric flexible film with reduced graphene oxide fillers. The generated voltages are higher and last longer than that in regular piezoelectric films. Photochemical crosslinking leads to a stable drug matrix which is even sustained in electric fields and high ionic strengths. The device enhances releases of positively, negatively, and zwitterionically charged molecules in response to mechanical stimuli and supports high cell viabilities. An illustrative application is demonstrated by preparing the material on the surface of a gastric lavage tube. The results show that the release of antiemetic drug increased by 200% within 60 min in response to forces mimicking human swallowing. This study contributes an integrative material that can realize electrically triggered releases that are previously only realized using complicated electrochemical setups. It is believed that this material can facilitate medicine applications in various emergent situations.

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“…It was demonstrated that films when subjected to 2 minutes of air plasma treatment gave optimum mechanical as well as barrier properties. Thus, depending on the need, air plasma treatment for different time periods can be given to the film for suitable use as packaging material [40]. On the other hand, starch/PBAT blend biodegradable films could be prepared by adopting two techniques based on blown extrusion method as reported by Brandelero et al PBAT was added to the starch polymer in order to give strength to the film.…”

Section: Starch Based Biodegradable Polymersmentioning

confidence: 99%

Recent Advances in Biodegradable Polymers

Dhamaniya¹,

Gupta²,

Kakatkar³

2018

J. Res. Updates Polym. Sci.

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Biodegradable polymers are important as an alternative to conventional non-degradable polymers for sustainable eco-system. The recent trends indicate that the new developments in biodegradable polymers focus on novel polymer systems that can cater the need of biomedical and packaging applications in-terms of performance and economics. The new interest is rapidly moving toward reducing carbon footprint through utilization of carbon dioxide and developing new methods of manufacturing such as 3D printing for specific purposes. This review focus on the present state-of-art and recent developments in biodegradable polymers covering their sources, synthetic methodologies, salient properties, degradation patterns, polymer blends and nanocomposites. As well as biodegradable polymers as a 3D printing material and the use of carbon dioxide as a renewable raw material for biomedical and packaging applications.

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The study of air-plasma treatment on corn starch/poly(ε-caprolactone) films

Cited by 43 publications

References 37 publications

3D-Printed Poly(ε-Caprolactone)/Hydroxyapatite Scaffolds Modified with Alkaline Hydrolysis Enhance Osteogenesis In Vitro

3D-Printed Poly(ε-Caprolactone)/Hydroxyapatite Scaffolds Modified with Alkaline Hydrolysis Enhance Osteogenesis In Vitro

A New Way to Promote Molecular Drug Release during Medical Treatment: A Polyelectrolyte Matrix on a Piezoelectric–Dielectric Energy Conversion Substrate

Recent Advances in Biodegradable Polymers

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