The Study of Antioxidant Capacity in Extracts from Vegetal Sources with Hypoglycaemic Action

Oláh, Neli-Kinga; Petrescu, Sorina; Marian, Eleonora; Jurca, Tünde; Marc, Felicia; Dobjanschi, Luciana; Honiges, Ana; Kiss, Rita; Bechir, Edwin Sever; Bechir, Farah; Ciavoi, Gabriela

doi:10.37358/rc.19.1.6860

Cited by 5 publications

(3 citation statements)

References 21 publications

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“…In addition, COVID-19 can bind to the angiotensin-converting enzyme 2 (ACE2) receptor in pancreatic β-cells thereby leading to pancreatic β-cell destruction, which in turn promotes the development of diabetes ( 29 ). Also, some natural products such as quercetin, curcumin or other hypoglycemic agents would participant in COVID-19 and diabetes research ( 30 – 32 ). Nevertheless, long-term follow-up studies are still needed to assess the impact of COVID on the incidence, type, and complications of diabetes.…”

Section: Discussionmentioning

confidence: 99%

The published trend of studies on COVID-19 and diabetes: bibliometric analysis

Li,

Peng,

2023

Front. Endocrinol.

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BackgroundSince the COVID-19 pandemic outbreak, diabetes mellitus (DM) has been at the core of the confirmed risk factors for fatal or critical care unit-treated COVID-19 and COVID-19 related complications. Although relevant studies on DM have developed rapidly during the COVID-19 pandemic. However, the aforementioned research results have not been systematically quantified by means of bibliometric analysis.PurposeThe purpose of this study is to provide a comprehensive analysis of the current status and trends of publications related to DM research during the COVID19 epidemic.MethodsA bibliometric analysis was performed using the Web of Science database. In this study, we used citespace, R software and R-Bibliometrix to analyze keywords, most-cited authors, most-cited countries, most-cited global documents, and co-occurrence and co-citation networks.ResultsA total of 1688 publications was included in this study. Investigators from the United States contributed the most publications. The United States, China and Europe have the most collaboration with the other countries/regions. A total of 3355 institutions made contributions to this study. Of the top 10 institutions with the most publications, N8 Research Partnership showed the most centrality. Among the top 10 journals, Diabetes Research and Clinical Practice published the most articles. Among authors included, Khunti Kamlesh is rated first with 27 papers and has the highest centrality. The most frequently co-cited article is entitled “Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study”. The most popular keywords included diabetes, mortality, diabetes, outcome, occurrences, risk, and type 1 diabetes.ConclusionThis bibliometric study provides an overall picture of DM research and research trends during the COVID-19 pandemic and provides a basis for researchers to develop their next research strategies.

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Section: Discussionmentioning

confidence: 99%

The published trend of studies on COVID-19 and diabetes: bibliometric analysis

Li,

Peng,

2023

Front. Endocrinol.

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“…Evaluation of the antioxidant activity of the extracts from EPF was performed by the DPPH spectrophotometric method in visible light at 517 nm [8,59]. Reduction reaction is made with antioxidants.…”

Section: Determination Of Free Radical Scavenging Activitymentioning

confidence: 99%

Determination of the Bioactive Compounds from Echinacea purpurea (L.) Moench Leaves Extracts in Correlation with the Antimicrobial Activity and the In Vitro Wound Healing Potential

et al. 2023

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This study aimed at the relationship between antioxidant capacity, antimicrobial activity, and in vitro evaluation of the wound healing effect of the extract obtained from Echinaceae purpureae folium (EPF). This study’s objective was to assess the bioactive components (total phenol and flavonoid content) and antioxidant activity of EPF extracts using the DPPH test method. The antioxidant capacity and the quantities of the compounds with antioxidant capacity were evaluated by spectrophotometric methods. Antimicrobial activity has been investigated against various pathogenic microorganisms. The minimum inhibitory concentration was determined by the microdilution method. Additionally, our work used a scratch test to examine the in vitro wound healing effects of EPF extract on NHDF cells. Statistical analysis was used to quantify the rate of migration and proliferation of fibroblast cells within the wound. Microscope pictures of fibroblast cells exposed to various EPF extract dosages were processed to estimate the width of the wound, area of the wound, and cell density inside the wound. The study proved that there was a relationship between the antioxidant, antimicrobial, and wound healing ability of EPF extracts.

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“…Briefly, 500 µL sample (six different concentrations) was mixed with 2500 µL DPPH 0.1 solution. The mixtures were allowed to stand for 30 min and then the absorbance was read at 517 nm [12].…”

Section: Antioxidant Activitymentioning

confidence: 99%

Risks and Benefits Associated with Tribulus terrestris Products Assessed by Phytochemical and Pharmacological Screening

Ștefănescu¹,

Zold²,

Mare³

et al. 2020

Rev. Chim.

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Recommendations of products with Tribulus terrestris as anabolic enhancers are based on empirical data. Exposure, especially of athletes, is very high, being among the most widely used nutritional supplements. Consumption of products containing Tribulus terrestris extracts has increased rapidly in the past few years due to the high content of sterol saponosides, compounds with presumed anabolic properties. Because of this upward surge, their efficacy and/or their safety are more and more often questioned. Commercialized dietary supplements, are often mislabelled, adulterated, or contaminated, therefore an evaluation of benefit/risk balance should always be conducted. Our study aimed to analyse an herbal drug and a food supplement frequently encountered on the market. Total polyphenolic and total saponosides content were determined. Inductively coupled plasma atomic emission spectrometry (ICP-AES) was used to determine mineral element content of Tribulus terrestris products. Antioxidant and antimicrobial activities were assayed. The extract obtained with the herbal drug had no antibacterial effect. The extract from the capsules, however, was active against all tested strains with higher activity against Methicillin-resistant Staphylococcus aureus and Escherichia coli (MIC = 0.78 mg/mL). Trace elements were quantified, and dose-related risks were outlined, raising awareness regarding the aluminum and nickel content in the herbal drug.

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The Study of Antioxidant Capacity in Extracts from Vegetal Sources with Hypoglycaemic Action

Cited by 5 publications

References 21 publications

The published trend of studies on COVID-19 and diabetes: bibliometric analysis

The published trend of studies on COVID-19 and diabetes: bibliometric analysis

Determination of the Bioactive Compounds from Echinacea purpurea (L.) Moench Leaves Extracts in Correlation with the Antimicrobial Activity and the In Vitro Wound Healing Potential

Risks and Benefits Associated with Tribulus terrestris Products Assessed by Phytochemical and Pharmacological Screening

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