The study of etiological profile in new onset seizures in Indian scenario

Rao, Bezwada Srinivasa; Vani, Matta Sree; Varma, Gedela Abhishek Ravi

doi:10.5455/2349-3933.ijam20150202

Cited by 7 publications

(8 citation statements)

References 15 publications

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“…Similar observation was made in studies by JNK Murthy; Jaishree T, Narayan, 8 Rao B.S., Vani M.S. and Varma, 7 while vascular causes were more frequent cause in study of developed nations. 13,14,15,16 Among 40 patients with cerebrovascular accidents accounts for 20% of all causes, stroke accounted for 35 (Infarct -20, Haemorrhage -15) followed by SAH in 2 patients, 1 each AV malformation and cerebral venous thrombosis (CVT).…”

Section: Discussionsupporting

confidence: 70%

“…While study done by Sriharsha K and Malali, 6 Narayanan J.T., Rao B.S., Vani M.S., Varma 7 and Murthy 8 reveal NCC (Neurocysticercosis) as most common neuroinfection.…”

Section: Discussionmentioning

confidence: 99%

“…These observations were similar to other Indian studies. 2,7,8 Neuroimaging was performed in all patients in our study. CT head was found normal in 116 patients, while abnormal in 84 patients.…”

Section: Discussionmentioning

confidence: 99%

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Clinico-Aetiological Spectrum of Seizure in Tertiary Care Hospital in Eastern Uttar Pradesh

Singh¹,

Khan²,

Chaudhary³

et al. 2016

jemds

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Section: Discussionsupporting

confidence: 70%

“…While study done by Sriharsha K and Malali, 6 Narayanan J.T., Rao B.S., Vani M.S., Varma 7 and Murthy 8 reveal NCC (Neurocysticercosis) as most common neuroinfection.…”

Section: Discussionmentioning

confidence: 99%

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Clinico-Aetiological Spectrum of Seizure in Tertiary Care Hospital in Eastern Uttar Pradesh

Singh¹,

Khan²,

Chaudhary³

et al. 2016

jemds

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“…In the developed world, trauma and space-occupying lesions (SOL) predominate, while the central nervous system (CNS) infections are the main causes of seizures in the developing world. [45] Antiepileptic drugs (AEDs) are indicated for most cases and need to be taken for many years. Compliance to these medications is a major concern and noncompliance is probably the most common cause of recurrent seizures.…”

Section: Introductionmentioning

confidence: 99%

Profile of patients presenting with seizures as emergencies and immediate noncompliance to antiepileptic medications

Honavar

Anuranjana

Markose

et al. 2019

J Family Med Prim Care

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Introduction:Seizure is a common manifestation of the many neurological conditions faced by primary care physicians. This study aims to determine the prevalence, etiology, and predictors of immediate noncompliance of adult patients presenting with seizures to the department of emergency (ED).Materials and Methods:We conducted this study in the ED of CMC, Vellore from November 2015 to February 2016. Retrospective chart review was used to gather specific data regarding these consecutive cases.Results:During the study period, 477 patients presented with seizures. The prevalence of nontrauma seizures in the ED was 2.3% [Figure 1]. The mean age was 41.4 ± 17.25 years. There was a male predominance (63.1%). About 11.7% had active seizures at presentation to the ED and less than a quarter (21.8%) were determined to have status epilepticus. Nearly 41% had new-onset seizures with common etiologies being idiopathic generalized epilepsy (22.6%), metabolic causes (17.9%), acute febrile illnesses (14.42%), and space-occupying lesions (12.3%). Among those with a history of seizures (58.9%), 87.9% were advised regular medications but 58.5% of them were immediately noncompliant. Phenytoin (58.6%), sodium valproate (20.5%), and levetiracetam (18%) were the most commonly used antiepileptics with 23% on multidrug therapy. About 60% were discharged stable from the ED. Univariate analysis showed chronic alcohol consumption (OR: 2.78; 95% CI: 1, 7.7) and female sex (OR: 1.45; 95% CI: 1–2.5) to be predictors of immediate noncompliance to antiepileptics.Conclusion:Common etiologies of new-onset seizures in the ED are idiopathic generalized epilepsy, metabolic causes, and acute febrile illnesses. More than half the patients with a known seizure disorder are immediately noncompliant to the advised medications. Knowledge among primary healthcare physicians about the importance of emphasizing compliance will greatly reduce the burden of seizures.

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“…The treatment of alcohol dependence is more important and should be prioritised before the prevention of further seizures. [5] [6] In small amounts alcohol does not cause seizures. Binge drinking and alcohol withdrawal can lead to seizures.…”

Section: Generalized Seizuresmentioning

confidence: 99%