This study examined the factors that affect the entrepreneurial intentions of university students in a developing economy. Drawing from the entrepreneurial orientation discourse and network approach, the study investigated the effect of innovativeness, proactiveness, risk-taking, and network ties on students' entrepreneurial intention. The study was conducted using 720 students selected from both private and public universities in Ghana. Data were collected using an online survey and analysed with partial least squares structural equation modelling (PLS-SEM) approach. The findings reveal that individual entrepreneurial orientation dimensions of innovativeness, risk-taking, and proactiveness influence entrepreneurial intentions. Also, the study found that network ties have a statistically significant effect on students' entrepreneurial intention. The type of university moderates the relationship between network ties, risk-taking behaviour, and entrepreneurial intentions. The findings of the study contribute to the development of policy and entrepreneurial education to enhance students' entrepreneurial intentions. Specifically, the findings imply that students' entrepreneurial development efforts must focus on their level of risk-taking behaviour, innovativeness, proactiveness, and network ties.