The article studies stability of intervening pillars at underground selective mining of complex structured ore bodies of Kryvyi Rih iron ore basin applying open stope systems that will enable the increased useful mineral component content in the mined ore mass. When calculating an exposure span, the current methods of determining room system constructive elements do not consider dirt thickness. So, it is essential to develop methods of determining room system constructive elements for mining complex structured ore bodies to provide stability of stope exposures. When mining a mine block, stoping is suggested to be fulfilled gradually from the footwall to the hanging wall of the ore body by room-and-pillar methods leaving a dirt or ore inclusion in the block. This enables decrease in concentrating tension and compression stresses in the middle part of the dirt or ore inclusion resulting in its 1.5-2.0 times greater stability. There is also determined that the stope stability is impacted by the horizontal thickness of the inclusion, the hardness ratio and the order of stoping in a mine block. Application of open stope methods in selective mining of complex structured ore bodies of Kryvyi Rih iron ore basin enables increased quality of the mined ore mass without significant capital and operating costs and results in better environment of the region.