The surface properties of nanocrystalline diamond and nanoparticulate diamond powder and their suitability as cell growth support surfaces

Lechleitner, Thomas; Klauser, Frederik; Seppi, Thomas; Lechner, Judith; Jennings, Paul; Perco, Paul; Mayer, Bernd; Steinmüller‐Nethl, Doris; Preiner, Johannes; Hinterdorfer, Peter; Hermann, Michael; Bertel, E.; Pfaller, Kristian; Pfaller, Walter

doi:10.1016/j.biomaterials.2008.07.023

Cited by 96 publications

(102 citation statements)

References 39 publications

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“…Moreover, the number of cells on the surface of hydrophilic NCD-o was significantly more than the control group and the NCD-h group. This result was consistent with the findings of scholars 16,17) , wherein someone confirmed that the surface of NCD-h would inhibit cell adhesion, they believed that was due to the lack of surface polar functional groups on the NCD-h surface, and the attachment of cells was the integration of cells and material surface 16) . Integrin-ligand complexes involved in cell adhesion and cell viability of the signaling, they combined the surface ligands of the material through the formation of focal adhesion 17) .…”

Section: Surface Characteristics Of Ncdsupporting

confidence: 91%

Characteristics of Nanocrystalline Diamond Films on Titanium Surface and its Impact on the Proliferation and Adhesion of Cells

Liu

Luo

et al. 2016

J. Hard Tissue Biology.

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Nanocrystalline diamond has extensive application in biology modified material aspects of human implants, because it has good mechanical properties such as corrosion resistance and biocompatibility. This study investigated the surface characteristics and biocompatibility of pure titanium whose surface was modified with nanocrystalline diamond by Microwave Plasma Chemical Vapor Deposition. Scanning electron microscope (SEM), Spectruman analysis ray diffraction and X-Ray photoelectron spectroscopy were used to analyze the chemical composition and surface topography of nanocrystalline diamond. We found that the particle size of the diamond on the titanium disc is nanocrystalline, and is without impure elements. In the experiment, we used Human Osteoblast-like cells MG63 to investigate the bioactivity of nanocrystalline diamond film. The attachment and proliferation of the cells were tested by NAPI, CCK-8. The result showed that oxygen terminated NCD groups had a significant advantage compared with hydrogen terminated and titanium groups on attachment and proliferation of MG63.

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Section: Surface Characteristics Of Ncdsupporting

confidence: 91%

Characteristics of Nanocrystalline Diamond Films on Titanium Surface and its Impact on the Proliferation and Adhesion of Cells

Liu

Luo

et al. 2016

J. Hard Tissue Biology.

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“…[36][37][38] The O-terminated diamond surface vanished after 400 o C annealing in vacuum. 39 While Thomas Lechleitner et al 40 Figure S1) As one of the source gases during CVD process, hydrogen makes the diamond grains H-terminated and such surface induces p-type surface conductivity. 41 This is in agreement with impedance measurement results, where the nanocrystalline diamond grains in p-type are more conductive than those in n-type O + -implanted films.…”

Section: (B)mentioning

confidence: 99%

An insight of p-type to n-type conductivity conversion in oxygen ion-implanted ultrananocrystalline diamond films by impedance spectroscopy

Coathup

et al. 2017

Applied Physics Letters

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The impedance spectroscopy measurements were used to investigate the separated contributions of diamond grains and grain boundaries (GBs), giving an insight of p-type to ntype conductivity conversion in O + -implanted ultrananocrystalline diamond (UNCD) films. It is found that both diamond grains and GBs promote the conductivity in O + -implanted UNCD films, in which GBs make at least half contribution. The p-type conductivity in O + -implanted samples is a result of H-terminated diamond grains, while n-type conductive samples is closely correlated to O-terminated O + -implanted diamond grains and GBs in the films. The results also suggest that low resistance of GBs is preferable to obtain high mobility n-type conductive UNCD film.

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“…All this allows the material to have a similar surface geometry of human bone. This type of structure and the morphological microstructural characteristics, as pointed out by Ripamonti (13), allow this material, just applied in situ, to absorb the full thickness bioactive proteins and growth factors present in the clot and releasing gradually, generating a rapid vascularization and making more effective osteogenesis (15,23,24). It has high osteoconductive properties and kinetics of osteointegration of 9-18 months (25)(26)(27).…”

confidence: 99%

“…Our research is directed precisely towards a biomaterial synthesis, the Engipore®, which is a bone substitute of the latest generation hydroxyapatite-based that possesses chemical and morphological properties very similar to those of natural bone. This type of structure and its morphological and microstructural characteristic allows this material, just applied in situ, to absorb the full thickness bioactive proteins and growth factors present in the clot and releasing gradually, generating a rapid vascularization and making more effective osteogenesis (15)(16)(17). It has high osteoconductive properties and kinetics of osseointegration of 9-18 months (2,3,18).…”

Section: Introductionmentioning

confidence: 99%

Histological evaluation of a biomimetic material in bone regeneration after one year from graft

Figliuzzi

Fazio

Tiano

et al. 2014

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SummaryAim. The use of substitute materials is one of the solutions used in periodontology for the reconstruction of intrabony defects. Advances in scientific research gave rise to a new generation of biomaterials of synthetic origin stoichiometrically unstable and therefore really absorbable. Our research is directed precisely towards a biomaterial synthesis, Engipore® (Finceramica, Faenza, Italy) which is a bone substitute of the latest hydroxyapatite-based generation, that possesses chemical and morphological properties similar to those of natural bone in the treatment of infrabony periodontal defects. Aim of this study was to evaluate the efficacy of Engipore® in the treatment of intrabony periodontal defects. Methods. The study was conducted on 100 parodontopatics patients, which had gingival pockets of at least infrabonies 8/10 mm. The histological evaluation was performed with samples after one year from the graft. Results. The histological samples collected after one year showed an abundant new bone formation, with mature lamellar bone tissue surrounding the residual particles of Engipore® that appear completely osteointegrated. The surrounding connective tissue shows no signs of inflammation. Conclusions. The results obtained in our researchdemonstrated that, after a proper selection of patients and lesions, and applying an adequate surgical technique, this type of biomaterial in the treatment of periodontal defects acts in an optimal manner as a filler inducing the formation of new bone as evidenced by histological examinations.

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The surface properties of nanocrystalline diamond and nanoparticulate diamond powder and their suitability as cell growth support surfaces

Cited by 96 publications

References 39 publications

Characteristics of Nanocrystalline Diamond Films on Titanium Surface and its Impact on the Proliferation and Adhesion of Cells

Characteristics of Nanocrystalline Diamond Films on Titanium Surface and its Impact on the Proliferation and Adhesion of Cells

An insight of p-type to n-type conductivity conversion in oxygen ion-implanted ultrananocrystalline diamond films by impedance spectroscopy

Histological evaluation of a biomimetic material in bone regeneration after one year from graft

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