The surgical management of facial nerve injury

Myckatyn, Terence M.; Mackinnon, Susan E.

doi:10.1016/s0094-1298(02)00102-5

Cited by 53 publications

(42 citation statements)

References 80 publications

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“…The hypoglossal (twelfth cranial nerve), facial (seventh cranial nerve) with crossface grafts, spinal accessory (eleventh cranial nerve), and phrenic nerves have all been transferred for facial reanimation with varying degrees of success. [1][2][3][4][5][6] The traditional nerve donor sites all possess a series of strengths and weaknesses, with no single transfer possessing the full complement of desirable characteristics, including limited donor-site morbidity, strong muscle contraction, rapid recovery, and an effortless or spontaneous smile.…”

mentioning

confidence: 99%

Facial Reanimation Using the Masseter-to-Facial Nerve Transfer

Klebuc

2011

Plastic and Reconstructive Surgery

137

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mentioning

confidence: 99%

Facial Reanimation Using the Masseter-to-Facial Nerve Transfer

Klebuc

2011

Plastic and Reconstructive Surgery

137

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“…While these few axons may have represented sprouts through the ETS repair, we could not clearly discern their origin with transcutaneous imaging. Collateral arbors may have also sprouted from the adjacent saphenous nerve territory to reduce the size of the denervated territory, a phenomenon that is noted clinically with the harvest of sensory nerve grafts Mackinnon 2003, Myckatyn andMackinnon 2004). …”

Section: Discussionmentioning

confidence: 99%

Axotomy or compression is required for axonal sprouting following end-to-side neurorrhaphy

Hayashi

Pannucci

Moradzadeh³

et al. 2008

Experimental Neurology

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End-to-side (ETS) nerve repair remains an area of intense scrutiny for peripheral nerve surgeonscientists. In this technique, the transected end of an injured nerve, representing the "recipient" is sutured to the side of an uninjured "donor" nerve. Some work suggests that the recipient limb is repopulated with regenerating collateral axonal sprouts from the donor nerve that go on to form functional synapses. Significant, unresolved questions include whether the donor nerve needs to be injured to facilitate regeneration, and whether a single donor neuron is capable of projecting additional axons capable of differentially innervating disparate targets. We serially imaged living transgenic mice (n=66) expressing spectral variants of GFP in various neuronal subsets after undergoing previously described atraumatic, compressive, or epineurotomy forms of ETS repair (n=22 per group). To evaluate the source, and target innervation of these regenerating axons, nerve morphometry and retrograde labeling was further supplemented by confocal microscopy as well as Western blot analysis. Either compression or epineurotomy with inevitable axotomy were required to facilitate axonal regeneration into the recipient limb. Progressively more injurious models were associated with improved recipient nerve reinnervation (epineurotomy: 184±57.6 myelinated axons; compression: 78.9±13.8; atraumatic: 0), increased Schwann cell proliferation (epineurotomy: 72.2% increase; compression: 39% increase) and cAMP response-element binding protein expression at the expense of a net deficit in donor axon counts distal to the repair. These differences were manifest by 150 days, at which point quantitative evidence for pruning was obtained. We conclude that ETS repair relies upon injury to the donor nerve.

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“…Pour Stricker [13] en 1981 le muscle est détaché dans ses deux tiers médians, le zygoma est échancré, le temporal peut aussi passer en arrière de l'arcade après exérèse de la boule graisseuse de Bichat. En 2003, Myckatyn et Mac Kinnon utilisent une technique voisine, prolongeant une bande musculaire par l'aponévrose temporale [54].…”

Section: Myoplastie Du Temporalunclassified

Histoire de la paralysie faciale

Glicenstein

2015

Annales de Chirurgie Plastique Esthétique

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The surgical management of facial nerve injury

Cited by 53 publications

References 80 publications

Facial Reanimation Using the Masseter-to-Facial Nerve Transfer

Facial Reanimation Using the Masseter-to-Facial Nerve Transfer

Axotomy or compression is required for axonal sprouting following end-to-side neurorrhaphy

Histoire de la paralysie faciale

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