The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site

Spinelli, Gian Paolo; Miele, Evelina; Tomao, Federica; Rossi, Luigi; Pasciuti, Giulia; Zullo, Angelo; Zoratto, Federica; Nunnari, Josè; Pisanelli, Giovanni Codacci; Tomao, Silverio

doi:10.1186/1477-7819-6-116

Cited by 10 publications

(4 citation statements)

References 17 publications

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“…Imatinib mesylate is a tyrosine kinase inhibitor that has shown a tumoral response greater than 50% (27), and it has been stablished as standard therapy for patients in whom a primary GIST has been resected (28), that is exactly the same therapy that was applied for this patient in 25 cycles.…”

Section: Discussionmentioning

confidence: 99%

COVID-19: Deciphering the cardiology riddle

Muñoz¹

2020

JCCI

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Retro-rectal tumors are a very rare entity in the adult population, with an incidence of approximately 1 in every 40.000-63.000 patients. Gastrointestinal Stromal Tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract.Clinical Case: 51-years-old patient with a clinical scenario of dysuria, vesical urgency and tenesmus, urinary retention, and constipation. Computer Tomography (CT) and Magnetic Resonance Imaging (MRI) shows a presacral mass. Pathology studies report GIST. Treated with abdominal resection and adjuvant therapy.Discussion: In 1983 the GIST was described with its origin in interstitial cells of Cajal, this tumor is more frequently found in the stomach, appearing in the 4 th decade of life and being abdominal pain the most common symptom, the more used diagnostic tools are still the CT and MRI, they let the physician decide which of the three approaching surgical methods is used. There are 3 histologic types GIST and the stratification of risk for each one is given based on tumor site, size, number of mitosis, and rupture.

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Section: Discussionmentioning

confidence: 99%

COVID-19: Deciphering the cardiology riddle

Muñoz¹

2020

JCCI

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“…GISTs usually arise from the stomach wall and extend inward toward the mucosa or outward toward the serosa, while pedunculated GIST is a unique pattern of growth that has rarely been reported [ 9 , 10 ]. Many GISTs are diagnosed after the onset of clinical symptoms including abdominal mass, pain, and bleeding [ 11 ]. However, occasionally they are discovered incidentally during the evaluation of other clinical entities [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

“…Concurrent occurrence of GIST and GEJ neoplasms is rare; only a few cases have been reported in the literature [ 3 ]. Spinelli et al reported a case with squamous cell carcinoma of the lower third of the esophagus with an incidental pathologic diagnosis of a concomitant GIST in the thoracic tract [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Coexistence of Primary GEJ Adenocarcinoma and Pedunculated Gastric Gastrointestinal Stromal Tumor

Alkaaki

Abdulhadi

Aljiffry

et al. 2018

Case Reports in Surgery

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Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive system, although they account for only 0.1–3% of all gastrointestinal (GI) malignancies. They can arise anywhere along the GI tract with gastric predominance. Concurrent occurrence of GIST and gastroesophageal junction (GEJ) neoplasm is rare. We report a 55-year-old gentleman presenting with a polyp at the GEJ and a synchronous, large, and pedunculated gastric mass at the greater curvature. Those were treated with a wedge resection of the gastric pedunculated mass with negative margins along with transgastric submucosal resection of the GEJ polyp. Pathological examination confirmed synchronous invasive GEJ adenocarcinoma and a high-grade gastric GIST.

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“…Esophageal tumors are usually small and asymptomatic, larger lesions present with dysphagia, and sometimes they may be found accidentally, as an abnormal mediastinal shadow on chest X-ray. Relevant literature reports only a few cases of these kinds of tumors, some treated with esophageal resection and others treated with enucleation (Spinelli GP et al;. …”

Section: Treatment Of the Non-metastatic Disease Approach To The Primmentioning

confidence: 99%

The Role of the Surgeon in Multidisciplinary Approach to Gastrointestinal Stromal Tumors

Sözen¹,

Topuz²,

Cihan³

2012

Gastrointestinal Stromal Tumor

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The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site

Cited by 10 publications

References 17 publications

COVID-19: Deciphering the cardiology riddle

COVID-19: Deciphering the cardiology riddle

Coexistence of Primary GEJ Adenocarcinoma and Pedunculated Gastric Gastrointestinal Stromal Tumor

The Role of the Surgeon in Multidisciplinary Approach to Gastrointestinal Stromal Tumors

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