The synthesis of chromophore ended glycoles, part IV. Bis-coumarin derivatives ended polyglycols

Abstract

The coumarin derivatives of bis‐resorcin ended polyglycols were prepared in two ways: Bis‐4‐alkyl‐7‐oxycoumarin ended mono and diethyleneglycols were prepared starting from bis(3‐hydroxyphenyl)glycols by coumarin condensation using relevant β‐ketoesters. Accordingly, 4‐methyl, 4‐trifluoromethyl, 4‐n‐propyl and 4‐phenyl derivatives of 7‐hydroxycoumarins were prepared in good yields. They were then converted to bis‐coumarin ended three and tetraethylenglycol derivatives by reacting with three and tetraethyleneglycols dichlorides in Na2CO3/DMF, respectively. The products were identified using IR, 1H nmr and low resolution mass spectrometry. The Li+, Na+ and Rb+ metal/Ligand selectivities of cation binding behaviour of products in acetonitrile were studied with steady state fluorescence spectroscopy.

Preparation of micrometer‐sized, multifunctional capsule particles for cosmetic by microsuspension polymerization utilizing the self‐assembling of phase separated polymer method

“…Synthesis of 7-N-(p-Vinylbenzyl)amino-4-methylcoumarin 7-Amino-4-methylcoumarin (1576.6 mg, 9.0 mmol), p-vinylbenzyl chloride (1376.1 mg, 9.0 mmol), sodium carbonate (953.9 mg, 9.0 mmol), dehydrated DMF (20 mL), and a Tefloncovered magnetic stirring bar were placed in a round-bottomed flask (50 mL) equipped with a reflux condenser. 8 The mixture was stirred at 85 C for 80 h. Water (50 mL) was added to the stirred solution. To precipitates collected by centrifugation, chloroform (200 mL) and water (100 mL) were added.…”