The synthesis of isomeric 4-prolinylamines and 4,4′-diprolinylamines

Yelin, E. A.; Onoprienko, V. V.; Kudelina, Irina A.; Мирошников, А. И.

doi:10.1007/bf02759631

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Elin et al obtained a synthetic argiopin. Such synthetic argiopin also passessed an ability to block the glutamate receptors [18].…”

Section: Tоксини з N Clavata і їхня хімічна структураmentioning

confidence: 99%

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Biologically active phenol and indole derivatives of terrestrial arthropods: electrophysiological and chemical characteristics

Klyuchko

2019

Biol. Stud.

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Klyuchko O.M. Biologically active phenol and indole derivatives of terrestrial arthropods: electrophysio logical and chemical characteristics. Studia Biolo gica, 2019: 13(2); 99-116 • DOI: https://doi. org/10.30970/sbi.1302.596Toxins-antagonists of glutamatergic synapses were found in venoms of different terrestrial Arthrpopodae, both Insecta and Aranei. Chemical structures of some of them were described, and a majority of such substances are derivatives of phenol and indole. They are used successfully for electrophysiological investigations of membrane structures, and present review is devoted to some results of such studies that may be useful for laboratory investigations. Here, we described chemical structure of some toxins, as well as the results of electrophysiological registration of activities of different venoms and toxins of Arthropodae. Hypotheses that explain physiological effects of the substances -antagonists of glutamate receptors depending on the peculiarities of their chemical structures are suggested. The role of different sites of toxins' molecules in blocking of glutamate receptors is discussed. The information about venoms' components of Insecta family Sphecidae (Philanthus triangulum), and of some Araneidae spider species of Argiope, Araneus, Nephila genera is also presented.

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“…Elin et al obtained a synthetic argiopin. Such synthetic argiopin also passessed an ability to block the glutamate receptors [18].…”

Section: Tоксини з N Clavata і їхня хімічна структураmentioning

confidence: 99%

“…Synthesis of JSTX-3 toxin and its four analogs with different polyamines' was conducted, and they all blocked the glutamate receptors [26]. A synthetic argiopin also possessed an ability to block the glutamate receptors [18].…”

Section: Role Of Different Sites Of Toxins' Molecules In Blocking Thementioning

confidence: 99%

Biologically active phenol and indole derivatives of terrestrial arthropods: electrophysiological and chemical characteristics

Klyuchko

2019

Biol. Stud.

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Approaches towards the development of chimeric DPP4/ACE inhibitors for treating metabolic syndrome

Sattigeri¹,

Sethi²,

Davis³

et al. 2017

Bioorganic & Medicinal Chemistry Letters

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The synthesis of isomeric 4-prolinylamines and 4,4′-diprolinylamines

Cited by 2 publications

References 7 publications

Biologically active phenol and indole derivatives of terrestrial arthropods: electrophysiological and chemical characteristics

Biologically active phenol and indole derivatives of terrestrial arthropods: electrophysiological and chemical characteristics

Approaches towards the development of chimeric DPP4/ACE inhibitors for treating metabolic syndrome

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