1967
DOI: 10.1021/jm00314a030
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The Synthesis of Some Aryl Nitrogen Mustard Derivatives of Estrogens

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“…The research efforts have mainly been focused towards reducing systemic toxicity and improving specificity of cancer therapy using lipophilic steroid nuclei as carriers to deliver the alkylating agents such as nitrogen and sulphur mustards to a specific target tissue with ease [2,3]. Further, as expected the synergistic activity out of these hybrid steroidal structures was also obtained.…”
Section: Introductionmentioning
confidence: 99%
“…The research efforts have mainly been focused towards reducing systemic toxicity and improving specificity of cancer therapy using lipophilic steroid nuclei as carriers to deliver the alkylating agents such as nitrogen and sulphur mustards to a specific target tissue with ease [2,3]. Further, as expected the synergistic activity out of these hybrid steroidal structures was also obtained.…”
Section: Introductionmentioning
confidence: 99%