“…The residues derived from the grape processing contain phytochemicals of interest for the production of preservatives, dyes, enriched foods, medicines, and products aimed at personal care, pharmaceutical, and cosmetic industries. The presence of bioactive compounds with antioxidant, antimicrobial, anti-inflammatory, anti-tumor, and protective activity of the cardiovascular system provides possibilities for many applications [ 221 ]. The potential beneficial role of phytochemicals of grape pomace in the prevention of disorders associated with oxidative stress and inflammation, such as endothelial dysfunction, hypertension, hyperglycemia, diabetes, and obesity, is due to the mechanisms concerned especially modulation of antioxidant/prooxidant activity, improvement of nitric oxide bioavailability, reduction of pro-inflammatory cytokines and modulation of antioxidant/inflammatory signal pathways [ 222 ].…”