The Tetralogy of Fallot

Sayed, Hamdy El; Bentall, H. H.; Melrose, D. G.

doi:10.1016/s0140-6736(62)91541-6

Cited by 6 publications

(2 citation statements)

References 5 publications

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“…With direct suture the stitches were placed as described by Sayed et al (1962) and tied over Teflon felt. In the very small heart three or four stitches were usually sufficient.…”

Section: Encephalogrammentioning

confidence: 99%

Total Correction of Tetralogy of Fallot in Young Children

McMillan¹,

Johnson²,

Machell³

1965

BMJ

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“…With direct suture the stitches were placed as described by Sayed et al (1962) and tied over Teflon felt. In the very small heart three or four stitches were usually sufficient.…”

Section: Encephalogrammentioning

confidence: 99%

Total Correction of Tetralogy of Fallot in Young Children

McMillan¹,

Johnson²,

Machell³

1965

BMJ

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“…Most of them focus on the tunability of size, shape and composition. For GNRs, a seed-mediated method pioneered by Murphy and El-sayed to fabricate kinds of GNRs with good monodisperse is so simple and effective that it has been adopted by most people [6][7]. The as-synthesized GNRs by this method are originally coated by CTAB used as surfactant in the procedure.…”

mentioning

confidence: 99%

Improving the biocompatibility and stability of gold nanorods(GNRs) as bioimaging tags through silica coating

Zhan

Qian

et al. 2009

2009 14th OptoElectronics and Communications Conference

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We report a facile method to coat GNRs by silica shell, which greatly improves GNRs' biocompatibility and chemical stability in applications without any obvious side effect on their attractive optical properties. Introduction Metallic (like gold and silver) nanoparticles which perform unique properties in bioimaging, biosensing and optical spectroscopy applications in biophotonics have attracted considerable attention in recent years [1]. These nanoscale metallic particles have also been employed as contrast agent in photoacoustic tomography (PAT), optical coherence tomography (OCT), magnetic resonance imaging (MRI) and optical imaging [2][3]. Due to the effect of photothermal such nanoparticles can also be applied to clinical therapy [4]. Like other metallic nanoparticles, gold nanorods (GNRs) also have unique optical properties (absorption and scattering) on account of localized surface plasmon resonance(LSPR), whose frequency greatly depends on GNRs' aspect ratio (length/diameter) and the refractive index of environmental medium, among many other factors [5]. Many more interesting applications based on LSPR of GNRs in surface plasmon enhanced scattering (SERS) sensor, SERS imaging, surface plasmon senor, fluorescence quenching and fluorescence enhancement are gradually emerging. It can be easily realized to get different LPSR frequency via tuning the aspect ratio of GNRs and different intensity of LSPR by controlling the separation distance.Considerable efforts have been made to explore the synthetic procedure of metallic nanoparticles in the past decade. Most of them focus on the tunability of size, shape and composition. For GNRs, a seed-mediated method pioneered by Murphy and El-sayed to fabricate kinds of GNRs with good monodisperse is so simple and effective that it has been adopted by most people [6][7]. The as-synthesized GNRs by this method are originally coated by CTAB used as surfactant in the procedure. The fact that CTAB-coated GNRs has high cytotoxicity and low stability has greatly blocked their wider applications in biophotonics. Common solution to this problem is to coat polymer on the surface of GNRs. However, these polymers have certain problems: hard to control thickness, bad optical effect, cytotoxicity and the like. It is desirable to obtain GNRs with highly sensitive, stable, biocompatible and targetable. Coating GNRs with silica shell may be a better choice. There are several attractive features of silica-coated GNRs, since silica is stable for encapsulation, optically transparent, water dispersible, biocompatible, nontoxic and easily modified to further bioconjugation [8]. Results and discussionsIn our experiments, the as-prepared GNRs were synthesized according to the protocol introduced by Xin Li et al [9][10]. A method reported by [11][12] was modified and carried out to realize the silica encapsulation. The pH value of 5ml GNRs solution was tuned to 10 by adding ammonia aqueous, and 800ul mixture of Tetraethoxysilane (TEOS) and anhydrous ethanol was added to the solution to start th...

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