Experimental and clinical studies relating psychological variables and allergic illness are summarized and critically reviewed. Special emphasis is given to methodological issues. The review, embracing principally English-language reports since 1950, focuses on respiratory allergy-asthma, rhinitis, hay fever.A SYCHOLOGICAL variables, viewed as etiological factors or as concomitant processes in allergic disease, have long been of speculative interest. Since 1950, the body of research and clinical reports relating psychological variables and allergic illness has grown rapidly. This paper will summarize and critically review this body of literature with the aim of integrating findings from diverse sources and methods. Special emphasis will be placed on methodological aspects in order to provide a focus for evaluating the current status of the area and to suggest profitable areas for future work.Mainly, papers in English dealing with psychological factors in respiratory allergy, published since 1950, are reviewed. Previous work has been comprehensively reviewed by Dunbar and Leigh; 37 however, certain influential earlier papers are included in the present review as points of orientation. A From the Allergy Department of the Kaiser Foundation Hospitals and the Permanente Medical Group, San Francisco, Calif. few papers from other languages also are discussed and are conceptually linked to investigations in English-speaking countries. The great size of this body of research dictates these limitations and the focus on respiratory allergy.