“…In 2022, Dadgar et al randomized men with idiopathic infertility, dividing them into four groups: pentoxifylline, zinc, p e n t o x i f y l l i n e + z i n c , a n d pl a c e b o . I n t h e z i n c a n d zinc + pentoxifylline groups, an improvement in terms of morphology and sperm DNA fragmentation was observed after 3 months of therapy (44). d) Vitamin supplementation is also considered a valid therapy for reducing oxidative stress in patients with high DFI, in particular vitamins D, E and C.…”