The toxic shock syndrome in burned children

Frame, James D.; Eve, Malcolm D.; Hackett, M.E.J.; Dowsett, E.G.; Brain, Anne; Gault, David; Wilmshurst, A.D.

doi:10.1016/0305-4179(85)90117-2

Cited by 98 publications

(15 citation statements)

References 8 publications

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“…We found only four cases (8%) secondary to burns, contrasting with previous published reports24 27 but consistent with a prestudy telephone surveillance of burns units (unpublished data). However, other skin-related sources made up 29% of cases.…”

Section: Discussionsupporting

confidence: 72%

Toxic shock syndrome surveillance in UK children

Adalat

Dawson

Hackett

et al. 2014

Archives of Disease in Childhood

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Section: Discussionsupporting

confidence: 72%

Toxic shock syndrome surveillance in UK children

Adalat

Dawson

Hackett

et al. 2014

Archives of Disease in Childhood

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“…Toxic shock syndrome was rare and only 42% of hospitals reported proven cases in the last two years (median 6) [11]. The number of cases between units varied widely and not all may comply with the recommended diagnostic criteria [6].…”

Section: Discussionmentioning

confidence: 99%

“…Staphylococcal toxic shock syndrome (TSS) is also uncommon but suspicion of the condition in scalded children is a frequent reason for starting antibiotic treatment in UK units [11]. Routine systemic antibiotic prophylaxis has largely been abandoned [9] but some have recommended the use of antibiotics to try to prevent these complications [8,11]. The use of short term antibiotics to cover burn wound excision is common in the USA but intraoperative bacteremia can be detected in up to 45% of patients despite prophylaxis [31].…”

mentioning

confidence: 99%

Wound management in burn centres in Europe

et al. 1995

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Infection remains a common cause of death in burned patients. A recent survey of UK burns units showed a range of opinion on the timing of burn wound excision and the use of therapeutic and prophylactic antibiotics. The same questionnaire was sent to other European burns units to assess their practice. Answers were obtained from 96 of the 164 units contacted. A written policy on antibiotic treatment was used by 35 (36%) units, imipenem being the single most popular antibiotic, but courses often lasted more than 10 days. Excisions were covered routinely by prophylactic antibiotics in 44 (45%) units, and 10 of these covered all procedures where the wound was manipulated. All units took surface swab cultures, and 26 (27%) took punch biopsies of the wounds. Silver sulphadiazine was used in 66 (69%) of the units while others preferred sulfamylon, povidone iodine or flamacerium. In 40 hospitals (42%) reporting proven cases of toxic shock syndrome, the median number was only six cases in two years. Nineteen (20%) excised burns within 48 hours of admission. The use of very broad spectrum antibiotics for prolonged courses was the most marked difference from the UK.

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“…The syndrome occurs with a number of conditions such as rhinoplasty, abdominoplasty, and breast augmentation [10,18]. TSS was described in children with burn injuries by Frame et al [7], and since then there have been many similar reports [6,4,11]. However, the syndrome has been reported only once, by Witney et al in 1999 [19], in an adult patient associated with burn injury.…”

Section: Introductionmentioning

confidence: 94%