The treatment of intrabony defects with bone grafts

Rosen, Paul S.; Reynolds, Mark A.; Bowers, Gerald M.

doi:10.1034/j.1600-0757.2000.2220107.x

Cited by 106 publications

(84 citation statements)

References 77 publications

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“…Periodontal regeneration refers to the restoration of supporting tissues of the teeth, which is the alveolar bone, cementum, and periodontal ligament to their original healthy levels before tissue destruction caused by periodontal pathogens has occurred. Histological examination of the newly formed tissues has to be done to establish that the regeneration has occurred (5,11,27). Currently, osseous grafting and guided tissue regeneration (GTR) are the two techniques with the most histological documentation of periodontal regeneration (15).…”

Section: Introductionmentioning

confidence: 99%

Surgical Treatment of Periodontal Intrabony Defects with Calcium Sulphate in Combination with Beta Tricalcium Phosphate – A 12-Month Retrospective Clinical Evaluation

Sukumar

Drízhal

Bukač

et al. 2010

Acta Med. (Hradec Kralove, Czech Repub.)

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Summary: Alloplastic bone graft materials are widely been used in combination with barrier membranes to achieve guided tissue regeneration in the treatment of periodontal intrabony defects. This study was designed to evaluate the clinical outcome of a composite material, beta tricalcium phosphate in combination with calcium sulphate in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. Thirty nine intrabony defects in 21 patients were treated with Fortoss ® Vital (Biocomposites, Staffordshire, UK). Clinical parameters were evaluated including changes in probing depth, clinical attachment level/loss and gingival recession at baseline and one year postoperatively. The mean differences in measurements between the baseline and one year postoperatively are a reduction of 1.98±1.16 mm (p=0.000) in case of probing depth and a gain of 1.68±1.12 mm (p=0.000) in clinical attachment level and an increase of 0.31±0.67 mm (p=0.009) in gingival recession measurements. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects one year postoperatively.

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Section: Introductionmentioning

confidence: 99%

Surgical Treatment of Periodontal Intrabony Defects with Calcium Sulphate in Combination with Beta Tricalcium Phosphate – A 12-Month Retrospective Clinical Evaluation

Sukumar

Drízhal

Bukač

et al. 2010

Acta Med. (Hradec Kralove, Czech Repub.)

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“…Rosen et al have indicated that it was easy to cause loosening (leading to failure) if the fibrous tissue growth wrapped the interface of the bone substitutes after implantation. 27 In our studies, new bone formed in the pores and connected with materials directly. Radiographic observations demonstrated that the grafting and non-lesion area combined as a whole.…”

mentioning

confidence: 99%

Analyzing the behavior of a porous nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite for healing of bone defects

Xiong

Ren

Zhang

et al. 2014

IJN

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The aim of this study was to analyze the behavior of the porous nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite grafted for bone defect repair through a series of biological safety experiments, animal experiments, and a more than 5-year long clinical follow-up. The biological safety experiments, carried out in accordance with the Chinese Guo Biao and Tolerancing (GB/T)16886 and GB/T16175, revealed that porous n-HA/PA66 composite had no cytotoxicity, no sensitization effect, no pyrogenic reaction, and that its hemolysis rate was 0.59% (less than 5%). Rabbit models of tibia defects with grafted porous n-HA/PA66 composite were established. After 2 weeks, the experiment showed that osteogenesis was detected in the porous n-HA/PA66 composite; the density of new bone formation was similar to the surrounding host bone at 12 weeks. After 26 weeks, the artificial bone rebuilt to lamellar bone completely. In the clinical study, a retrospective review was carried out for 21 patients who underwent serial radiographic assessment after treatment with porous n-HA/PA66 composite grafts following bone tumor resection. All wounds healed to grade A. No postoperative infections, delayed deep infection, nonspecific inflammation, rejection, or fractures were encountered. At a mean follow-up of 5.3 years, the mean Musculoskeletal Tumor Society’s (MSTS) 93 score was 29.3 points (range: 28–30 points) and mean radiopaque density ratio was 0.77±0.10. The radiologic analysis showed that porous n-HA/PA66 composite had been completely incorporated with the host bone about 1.5 years later. In conclusion, this study indicated that the porous n-HA/PA66 composite had biological safety, and good biocompatibility, osteoinduction, and osseointegration. Thus, the porous n-HA/PA66 composite is an ideal artificial bone substitute and worthy of promotion in the field.

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“…(TABLE-3 The primary goal of periodontal therapy is to arrest the progression of periodontal disease and maintain the natural dentition for esthetics and function. If periodontal disease results into a loss of the attachment apparatus, attempts are made to regenerate the periodontium to a pre-diseased state (12) . Though periodontal regeneration continues to be the ultimate goal of periodontal therapy, outcome is dependent on multiple factors.…”

Section: Bone Density Fillmentioning

confidence: 99%

Perioglas® And Prf As Graft Materials in The Treatment of Intrabony Defects in Chronic Generalized Periodontitis: A Clinical And Radiological Evaluation

Singh¹,

Chandrashekar²,

Mishra³

et al. 2016

IOSR

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The treatment of intrabony defects with bone grafts

Cited by 106 publications

References 77 publications

Surgical Treatment of Periodontal Intrabony Defects with Calcium Sulphate in Combination with Beta Tricalcium Phosphate – A 12-Month Retrospective Clinical Evaluation

Surgical Treatment of Periodontal Intrabony Defects with Calcium Sulphate in Combination with Beta Tricalcium Phosphate – A 12-Month Retrospective Clinical Evaluation

Analyzing the behavior of a porous nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite for healing of bone defects

Perioglas® And Prf As Graft Materials in The Treatment of Intrabony Defects in Chronic Generalized Periodontitis: A Clinical And Radiological Evaluation

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