The Treatment of Leishmaniasis Recidivans With Local Injections of Amphotericin B

Successful Treatment of Lupoid Cutaneous Leishmaniasis with Glucantime and Topical Trichloroacetic Acid (A Case Report)

“…Treatment options include intraregional pentavalent antimony [11], a combination therapy with intramuscular injection of meglumine antimoniate (MA) and allopurinol [12], local injection of amphothericin B [13], levamisole [14], dapsone [15], cryotherapy [16], and triple therapy with paromomycin, cryotherapy, and intralesional meglumine antimoniate [5]. …”

The therapeutic effect of combined cryotherapy, paramomycin, and intralesional meglumine antimoniate in treating lupoid leishmaniasis and chronic leishmaniasis

“…Many therapeutic regimens with different efficacies have been proposed for these two forms of leishmaniasis (i.e., lupoid and chronic). Some of these therapeutic modalities are combined intramuscular injection of meglumine antimoniate (MA) and allopurinol, 7 local injection of amphothericin B, 8 levamizole, 9 dapsone, 10 cryotherapy, 11 and intravenous injection of sodium stibogluconate 12…”

Comparison of Lesion Improvement in Lupoid Leishmaniasis Patients with Two Treatment Approaches

“…5,6 The most accepted medical treatment of CL is pentavalent antimonial antimoniate compounds such as meglumine antimoniate (MA; Glucantime) and sodium stibogluconate (Pentostam), which are administered systemically or intralesionally, and/or as combination therapy with other treatments, such as alloporinol or amphotericin. 7,8 This regimen must be used for several weeks, and, unfortunately, it has many unwanted side effects. On the other hand, several physical therapeutic methods are available, including CO 2 laser, cryotherapy, thermotherapy, and trichloroacetic acid (TCA).…”