2022
DOI: 10.1111/trf.16951
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The U.S. Armed Services Blood Program support to U.S. Central Command 2014–2021: Transformation of combat trauma resuscitation through blood product innovation and expansion of blood availability far forward

Abstract: Background The United States Armed Services Blood Program (ASBP) faced complex blood supply challenges during two decades of military operations in the U.S. Central Command (CENTCOM) and through an adaptive, responsive, and agile system, gained valuable insights on blood product usage in combat casualty care. Study Design and Methods A retrospective review of blood product introduction and utilization trends was compiled from ASBP data collected during CENTCOM operations from 2014 through 2021. Results During … Show more

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Cited by 10 publications
(12 citation statements)
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“…(2) Stored WB (SWB); refers to FWB refrigerated at 1°C to 6°C within 8 hours of collection in either citrate-phosphate-dextrose (CPD) (shelf life, 21 days) or citrate-phosphate-dextrose-adenine-1 (CPDA-1) (shelf life, 35 days). 30 (3) Low Titer type O Whole Blood (LTOWB); WB type O with low titer IgM anti-A and anti-B (titer <1:256). 31 Blood component transfusion was defined as red blood cell (RBC) transfusion with or without plasma and/or platelet transfusion.…”
Section: Definitionsmentioning
confidence: 99%
“…(2) Stored WB (SWB); refers to FWB refrigerated at 1°C to 6°C within 8 hours of collection in either citrate-phosphate-dextrose (CPD) (shelf life, 21 days) or citrate-phosphate-dextrose-adenine-1 (CPDA-1) (shelf life, 35 days). 30 (3) Low Titer type O Whole Blood (LTOWB); WB type O with low titer IgM anti-A and anti-B (titer <1:256). 31 Blood component transfusion was defined as red blood cell (RBC) transfusion with or without plasma and/or platelet transfusion.…”
Section: Definitionsmentioning
confidence: 99%
“…Massive hemorrhage has been previously described as the most common preventable cause of death on the battlefield 1 . Military guidelines have since pivoted to prioritize hemorrhage control and pre‐hospital fluid resuscitation 2,3 . While cold‐stored, Food and Drug Administration (FDA)‐compliant whole blood is the preferred product for trauma resuscitation, activation of the walking blood bank (WBB) may be used to obtain fresh whole blood for emergency transfusion when supplies have been depleted.…”
Section: Introductionmentioning
confidence: 99%
“…1 Military guidelines have since pivoted to prioritize hemorrhage control and pre-hospital fluid resuscitation. 2,3 While cold-stored, Food and Drug Administration (FDA)compliant whole blood is the preferred product for trauma resuscitation, activation of the walking blood bank (WBB) may be used to obtain fresh whole blood for emergency transfusion when supplies have been depleted. However, ensuring the absence of TTIs from WBB products has remained a vexing challenge given the logistical difficulties of meeting FDA standards for testing in the deployed environment.…”
Section: Introductionmentioning
confidence: 99%
“…Prehospital resuscitation with whole blood is critical in combating morbidity and mortality associated with hemorrhagic shock 1–4 . The military has made great effort to provide early resuscitation with the golden hour, 5,6 low titer group O whole blood (LTOWB), 7,8 and “walking blood bank”/“buddy transfusion” programs 9–12 . Unfortunately, blood still remains scarce in the prehospital setting due primarily to the logistics involved in distribution and delivery to the site of trauma coupled with its perishability.…”
mentioning
confidence: 99%
“…[1][2][3][4] The military has made great effort to provide early resuscitation with the golden hour, 5,6 low titer group O whole blood (LTOWB), 7,8 and "walking blood bank"/"buddy transfusion" programs. [9][10][11][12] Unfortunately, blood still remains scarce in the prehospital setting due primarily to the logistics involved in distribution and delivery to the site of trauma coupled with its perishability. Whole blood can be kept in an insulated container for short periods, but longer durations outside of proper refrigeration storage typically means temperature excursions resulting in nonviability of the product.…”
mentioning
confidence: 99%