The ultrastructure of normal squamous epithelium of the human cervix uteri

Hackemann, Margaret; Grubb, Chandra; Hill, K. R.

doi:10.1016/s0022-5320(68)90033-6

Cited by 80 publications

(28 citation statements)

References 21 publications

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“…Dendritic cells comprise a system that occupies discrete portions of nonlymphoid and lymphoid organs (Steinman, 1991). Langerhans and interstitial dendritic cells constitute the dendritic cell system in nonlymphoid organs (Steinman, 1991 (Birbeck et al 1961;Breathnach, 1964) but nose (Jahnke, 1974), oral cavity (Schroeder and Theilade, 1966) and cervix uteri (Hackermann et al 1968) Thompson and Griffin (1994) reported Langerhans cells in normal and pathological vocal folds, using the S-100 polyclonal antibody. Regarding the hypopharynx, Langerhans cells in it were little reported.…”

Section: Morphologic Findings Of the Langerhans Cells In The Larynx Amentioning

confidence: 99%

Langerhans Cells in the Larynx and the Hypopharynx.

Sato

Hirano

1997

Kurume Med. J.

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Summary: Langerhans cells are important in the human immune system as a part of the dendrtic cell system. This study was carried out to demonstrate the presence of Langerhans cells and their distribution in normal human larynx and hypopharynx, by light (S-100 polyclonal antibody) and transmission electron microscopy. The results are summarized as follows: 1) Langerhans cells with cytoplasmic granules (Langerhans granules or Birbeck's granules) were situated in the suprabasal region of the squamous epithelium in the larynx and the hypopharynx. 2) They distributed in the membranous portion of the vocal folds, epiglottis, aryepiglottic folds, arytenoid regions and interarytenoid notch of the larynx. The cells surrounded the vestibule and glottis of the larynx. 3) They distributed in the postcricoid area, piriform sinus and posterior pharyngeal wall of the hypopharynx. The cells were situated above the entrance of esophagus. 4) The cells were suggested to be a factor of immune response at the entrance of trachea and esophagus. Key wordsLangerhans cell, immunology of larynx and hypopharynx, histology of larynx and hypopharynx, vocal folds, larynx, hypopharynx

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Section: Morphologic Findings Of the Langerhans Cells In The Larynx Amentioning

confidence: 99%

Langerhans Cells in the Larynx and the Hypopharynx.

Sato

Hirano

1997

Kurume Med. J.

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“…The cells in the uterine glands were columnar or triangular in shape with their single process directed towards the lumen [ [13,14]. Langerhans cells appear to form a relatively constant component of both the transformation zone and exocervical epithelium [15].…”

Section: Resultsmentioning

confidence: 99%

Morphological Study of Dendritic Cells in Human Cervix by Zinc Iodide Osmium Method

Rabi

Lionel

Indrasingh

2014

JCDR

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“…Considered from these findings, the superficial cells appear to represent the transitional stage in the keratinizing process, and have morphologically close resemblance to both the granular cells and the cornified ones in keratinized epithelia. In the epithelium lining the human cervix uteri, which did not normally keratinize but had ability of keratinization under certain pathological conditions, Hackemann et al (1968) reported that the superficial cells contained keratohyalin granules and were characterized by a marked thickening of the inner leaflet of the plasma membrane. They also described that the majority of the tonofilaments were concentrated near the cell borders, but extremely small nucleus, degenerating mitochondriaand lysosome-like bodies were remained (Hackemann et al, 1968).…”

Section: Discussionmentioning

confidence: 99%

“…In the epithelium lining the human cervix uteri, which did not normally keratinize but had ability of keratinization under certain pathological conditions, Hackemann et al (1968) reported that the superficial cells contained keratohyalin granules and were characterized by a marked thickening of the inner leaflet of the plasma membrane. They also described that the majority of the tonofilaments were concentrated near the cell borders, but extremely small nucleus, degenerating mitochondriaand lysosome-like bodies were remained (Hackemann et al, 1968). It is suggested that the superficial cells in the human cervix uteri appear to correspond to the superficial cells in this study if not exact structure, and that the structural differences between these 2 cells are attributed to the difference of the degree of keratinization.…”

Section: Discussionmentioning

confidence: 99%