“…Ti-6Al-4V which has higher mechanical strength, young modulus almost equal to human bones thus reducing the shielding effect, extending the life of implant material, and non-toxic. [1] Problems that arise in implant production are the success parameters of titanium implants indicated by the effectiveness of interactions between biomaterials and tissues, influenced by several factors, including the composition of implant surfaces, implant morphology, and roughness of implant surfaces [2,3]. Implant failure still occurs, Mechanical loosening, until the infection associated with this implant still poses a serious threat that leads to possible complications such as prolonged hospitalization, complicated revision procedures, implant failure, complete removal, patient suffering, to financial burden [4].…”