The use of an innovative inverse numerical modeling method for the evaluation and parameter estimation of barberry anthocyanins ultrasound assisted extraction

A Mechanistic Model of Mass Transfer in the Extraction of Bioactive Compounds from Intact Sorghum Pericarp

“…The development of extraction methods to obtain phytochemical compounds from plants as a source of food supplements and medicines remains attractive [1][2][3][4]. Several methods have been applied to improve the extraction process in the pharmaceuticals and food industry [5,6].…”

“…The antioxidant activity of proanthocyanidins has been evaluated on the basis of their radical scavenging activity in 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assays, iron (II) chelating ability (ICA), and oxygen radical absorbance capacity (ORAC) [8]. As powerful antioxidant and antibacterial agents, these compounds are very useful as diet supplements, medicines, nutraceuticals, pharmaceuticals [10], pigments, and food additives to preserve food quality from deterioration and rancidity [1,2].…”

“…Furthermore, some studies focused on designing new methods of extraction that were safe, cheap, efficient, and effective in producing extracts in a high quantity and of high quality [4,8,[15][16][17][18][19]. Several techniques were developed to obtain standard extraction procedures to be applied for the extraction of functional compounds to meet the needs of the pharmaceutical, food, and chemical industries [1,9,[20][21][22].…”

“…Commonly, the extraction of bioactive compounds from sorghum is carried out while using conventional methods that apply hot water and maceration to sorghum bran [9,19]. Maceration and hot water extraction are basic methods of solid-liquid extraction for separating and isolating active compounds from their original locations in the plant body [1] as well as for transferring them into the solvent, a process that is usually driven by natural convection. These methods use solvents in which the solid material is immersed.…”

“…Numerical solution has commonly been applied as a method for complex models [1,26]. The important involved parameters in extraction can be estimated through simulation by utilizing the developed mathematical model [2].…”