“…These data suggest pathogenic justification for use of anaferon – a drug containing ultra-high dilutions of affinity-purified antibodies to human IFN-γ as the active pharmaceutical ingredient – in the complex treatment of schizophrenia. Previously, it has been found that medication produces an immunomodulating effect: increases initially low IFN-γ levels, normalises elevated levels of IL-1β, optimises the Th1/Th2 balance of immune response, exerting ‘sparing’ therapeutic effect (16,17). The paper reports of the first ever experience of using anaferon as an additional drug in complex antipsychotic therapy of patients with schizophrenia, which is supported by a patent (20).…”