1990
DOI: 10.1007/bf00841437
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The use of avidin to accelerate blood clearance of biotinylated immunogobulins

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Cited by 3 publications
(2 citation statements)
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“…Specific highaffinity interaction between these compounds has been employed in various immobilization systems (as 'cross-linking' and 'staining' agents etc.). Some researchers attempted to apply the avidin-biotin pair in vivo to the gamma-scintigraphic technique [17], acceleration of the clearance of labelled proteins in the circulation [18,19] and drug targeting [20]. However, the effects of biotin-avidin or of components carrying this pair on the effector systems of the organism are poorly understood.…”
Section: Discussionmentioning
confidence: 99%
“…Specific highaffinity interaction between these compounds has been employed in various immobilization systems (as 'cross-linking' and 'staining' agents etc.). Some researchers attempted to apply the avidin-biotin pair in vivo to the gamma-scintigraphic technique [17], acceleration of the clearance of labelled proteins in the circulation [18,19] and drug targeting [20]. However, the effects of biotin-avidin or of components carrying this pair on the effector systems of the organism are poorly understood.…”
Section: Discussionmentioning
confidence: 99%
“…IgG were chosen because they do not cross vascular wall and circulate in the blood for a long time period [7].…”
mentioning
confidence: 99%