The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications

Abstract

Bioglass has been used for bone-filling material in bone tissue engineering, but its lean mechanical strength limits its applications in load-bearing positions. Carbon nanotubes (CNTs), with their high aspect ratio and excellent mechanical properties, have the potential to strengthen and toughen bioactive glass material without offsetting its bioactivity. Therefore, in this research, multiwall carbon nanotube (MWCNT)/45S5 Bioglass composite scaffolds have been successfully prepared by means of freeze casting process. 45S5 Bioglass was synthesized by the sol-gel processing method. The obtained material was characterized with X-ray powder diffraction (XRD). The mechanical properties of the scaffolds, such as compression strength and elastic modulus, were measured. Finally, compared with the scaffolds prepared by 100% 45S5 Bioglass powders, the addition of 0.25 wt.% MWCNTs increases the compressive strength and elastic modulus of 45S5 Bioglass scaffolds from 2.08 to 4.56 MPa (a 119% increase) and 111.50 to 266.59 MPa (a 139% increase), respectively.

Ice-Templated Porous Nanocellulose-Based Materials: Current Progress and Opportunities for Materials Engineering

“…The ice-templating process has already been used to fabricate a wide variety of porous materials with a great potential in several engineering fields [63], including construction [69], energy [70], and biomedical [71,72] sectors. In comparison to other processes, ice-templating routes exhibit several unique features.…”

Nanoparticles for bone tissue engineering

“…Nanotechnology has made it possible to create structures within the same size as those that constitute naturally occurring bone, opening a new era for TERM. Hence, nanoparticles (NPs) can be used to modify scaffolds properties, leading to enhanced characteristics such as superior mechanical properties and osteointegration, osteoconduction, and osteoinduction . Moreover, NPs can be applied to deliver drugs in a controlled and dependent manner, either systemically or locally .…”

Kesan Kandungan Fosfat Berbeza terhadap Pembentukan Morfologi Permukaan, Penghabluran, Fasa, Ikatan Kimia dan Kekuatan Mampatan Bio-kaca Sol-Gel Tersinter

“…Peratus penghabluran yang diperoleh menunjukkan sebahagian besar fasa kaca telah menghablur namun bukan merupakan penghabluran penuh. Kajian sebelum ini melaporkan bahawa kebolehupayaan sinteran kaca sol-gel adalah agak rendah dan sekaligus membawa kepada kesukaran untuk membentuk penghabluran penuh (Touri et al 2013).…”