The Use of cDNA Cloning Techniques to Isolate Genes Activated in Tumour Cells

We have used differential cDNA cloning techniques to isolate a number of genes that are activated as a result of transformation by the DNA tumour virus Simian virus 40. From the nucleotide sequences of the cDNA clones we have been able to identify some of these genes. One of them derives from the major histocompatibility complex and contains a repetitive element that identifies a large number of RNAs present in pluripotential embryonic cells.

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The activation of cellular genes in transformed cells

Rigby

Brickell

Latchman

et al. 1984

Phil. Trans. R. Soc. Lond. B

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The Use of cDNA Cloning Techniques to Isolate Genes Activated in Tumour Cells

Cited by 1 publication

References 13 publications

The activation of cellular genes in transformed cells

The activation of cellular genes in transformed cells

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