The Use of Graft Materials and Platelet Rich Plasma in Oral Surgery

Dimova, Cena; Evrosimovska, Biljana; Поповска, Мирјана

doi:10.4028/www.scientific.net/ddf.376.39

DDF

2017

DOI: 10.4028/www.scientific.net/ddf.376.39

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The Use of Graft Materials and Platelet Rich Plasma in Oral Surgery

Cena Dimova

Biljana Evrosimovska

Мирјана Поповска

Abstract: The aim of this paper is to highlight the classification and indications of different bone grafting materials and barrier membrane for everyday clinical practice of contemporary work in the field of oral surgery and periodontology. Number of different growth factors are used together with graft materials. Among these are platelet rich plasma (PRP) and platelet-rich fibrin (PRF). With the simplified technique, an autologous fibrin matrix, which contains platelets and leucocyte growth factors, is acquired.

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Cited by 2 publications

References 91 publications

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Study on repairing canine mandibular defect with porous Mg–Sr alloy combined with Mg–Sr alloy membrane

Zhang¹,

Sun²,

Kang³

et al. 2020

Regenerative Biomaterials

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To discuss the feasibility of the application of porous Mg–Sr alloy combined with Mg–Sr alloy membrane in the repair of mandibular defects in dogs. The second and third mandibular premolars on both sides were extracted from six dogs. The model of mandible buccal fenestration bone defects were prepared after the sockets healed. Twelve bone defects were randomly divided into groups A and B, then Mg–Sr alloy was implanted in bone defects of group A and covered by Mg–Sr alloy membrane while Mg–Sr alloy was implanted in bone defects of group B and covered by mineralized collagen membrane. Bone defects observed on cone beam computed tomographic images and comparing the gray value of the two groups after 4, 8 and 12 weeks. After 12 weeks, the healing of bone defects were evaluated by gross observation, X-ray microscopes and histological observation of hard tissue. Bone defects in each group were repaired. At 8 and 12 weeks, the gray value of group A was higher than that of group B (P < 0.05). At 12 weeks, the bone volume fraction of group A was higher than that of group B (P < 0.05). The newly woven bone in group A is thick and arranged staggered, which was better than that of group B. Porous Mg–Sr alloy combined with Mg–Sr alloy membrane could further promote the repair of mandibular defects, and obtain good osteogenic effect.

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Study on repairing canine mandibular defect with porous Mg–Sr alloy combined with Mg–Sr alloy membrane

Zhang¹,

Sun²,

Kang³

et al. 2020

Regenerative Biomaterials

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show abstract

From Hematology to Tissue Engineering: Current Status and Projection of Platelet Concentrates and their Derivatives

Velásquez¹,

Gamboa

2022

Univ Odontol

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Background: In the last decade, tissue engineering, cell therapy, and research advances in hematological sciences have become tools for regenerative dentistry, using platelet concentrates as the cornerstone. The results are promising, but it is necessary to consolidate the existing evidence on their real relevance and clinical impact. Purpose: To conduct an integrative review of literature to present scientific evidence on platelet concentrates, their use, characteristics, benefits, and usefulness for tissue engineering. Methods: The search for information was performed in the integrated search engine EBSCOhost, including studies published from 2010 to early 2020. Results: Most of the publications present the evolution of platelet concentrates with evaluations of their in vitro and in vivo use, clinically proving their regenerative potential in soft tissue and bone repair. Marked differences exist between platelet-rich plasma and platelet-rich fibrin. Conclusion: There is controversy and indiscriminate use of the terminology referring to platelet concentrates; however, they are not only a source of growth factors, but also a living biomaterial, based on fibrin, and its positioning as a surgical material is increasingly evident to become a tissue-oriented solution, by optimizing regeneration and healing, and an important tool of low economic profile in tissue engineering.

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The Use of Graft Materials and Platelet Rich Plasma in Oral Surgery

Cited by 2 publications

References 91 publications

Study on repairing canine mandibular defect with porous Mg–Sr alloy combined with Mg–Sr alloy membrane

Study on repairing canine mandibular defect with porous Mg–Sr alloy combined with Mg–Sr alloy membrane

From Hematology to Tissue Engineering: Current Status and Projection of Platelet Concentrates and their Derivatives

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