The construction sector is regarded as an economic sector that plays an important role in driving the country's economy, especially in infrastructure development and urban development. Similarly, construction section has vital important in Bangkok, Thailand. However, the promotion of entrepreneur’s success in construction business is one of the challenges. Several businesses could not get success in the competitive market. In this way, the current study is an attempt to investigate the role of spiritual leadership, contractor’s attitudes towards risks, management innovation and organizational culture on business entrepreneurs’ success in construction industry. A mixed method approach is used in this study in which the data collection is made through questionnaire and in-depth interviews. Structural Equation Modeling (SEM) is employed to analyze the data. It is found that; spiritual leadership, contractor’s attitudes towards risks, management innovation and organizational culture has major influence on business entrepreneurs’ success in construction industry of Bangkok, Thailand.