The influences of cosmic radiation on atoms and molecules in the Earth's atmosphere were observed with subsequent transformation of atoms, molecules of gases, as well as development of states of oxygen deficiency (hypoxic) in biological organisms, some recommended ways of such disorders correction. Purposes of this work were to study radiation effects in ionosphere with subsequent high-energy transformations of atoms, molecules of gases at different heights above the Earth surface; interaction of some high-energy atmospheric particles with biological objects at near Earth's heights up to 5.500 m above sea level (a.s.l.), and oxygen roles in consequences of biological organisms’ irradiation. Methods. Analysis of results of satellite and rocket observations of the Earth atmosphere gases exploring at different altitudes a.s.l. Investigations in mountain conditions at EMBS research station of the National Academy of Sciences of Ukraine: comparative analysis of results of long-term observation of patients using standard laboratory methods, complex of methodological techniques: clinical, physiological studies of respiratory, cardiovascular systems; hematological, immunological states; functional state of higher nervous activity, mental and neurotic state; antihypoxants use, histochemical, biophysical methods, math modelling, others. Results. The last data obtained during the satellites atmosphere exploring were presented: studies of influences on the structure of atoms, molecules in atmosphere, concentrations of gases from ionosphere to the Earth surface, such phenomena as photochemical processes, photoionization. The notion “information” was discussed basing on phenomena, described in the article. Described studies of gases particles modification, oxygen deficiency in organisms (hypoxic states) were supplemented with the results of irradiated Chernobyl patients’ examinations, rehabilitation by Ukrainian doctors, scientists in mountain conditions. Conclusions. Phenomena of solar radiation influence on atoms, molecules and molecular complexes in the Earth's atmosphere were observed. The main attention was concentrated on the studies of gases concentrations at different heights with linked effects of oxygen roles in consequences of organisms’ irradiation and rehabilitation. Practical recommendations for patients’ medical care and rehabilitation were done.