2016
DOI: 10.2147/vmrr.s112200
|View full text |Cite
|
Sign up to set email alerts
|

The use of meloxicam oral suspension to treat musculoskeletal lameness in cattle

Abstract: Lameness in beef and dairy cattle is responsible for economic losses and has significant animal welfare implications. It has been proposed that early treatment with analgesics not only reduces acute pain but also leads to reduced long-term sensitization. Fifty-three cattle (309–954 kg body weight [BW], mean: 656 kg) with musculoskeletal lameness were scored for lameness and inflammation, then randomly assigned to a single oral treatment with meloxicam oral suspension (MOS) (28 animals) at 1 mg/kg or saline at … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

1
4
0

Year Published

2017
2017
2024
2024

Publication Types

Select...
5
1

Relationship

1
5

Authors

Journals

citations
Cited by 6 publications
(6 citation statements)
references
References 12 publications
1
4
0
Order By: Relevance
“…Results of the current study are supported by other studies that found a positive milk production response following NSAID administration at calving, though the milk response was not as pronounced as previous studies have noted [9,10,14,15,16]. Conversely, some studies evaluating the effect of analgesia following calving have failed to find an association with increased milk production [17,18]; however, these studies only evaluated daily milk production over the first 2 weeks of lactation; whereas, studies that found associations between meloxicam treatment and daily milk production increases evaluated production over a far longer period of time.…”
Section: Discussionsupporting
confidence: 86%
See 1 more Smart Citation
“…Results of the current study are supported by other studies that found a positive milk production response following NSAID administration at calving, though the milk response was not as pronounced as previous studies have noted [9,10,14,15,16]. Conversely, some studies evaluating the effect of analgesia following calving have failed to find an association with increased milk production [17,18]; however, these studies only evaluated daily milk production over the first 2 weeks of lactation; whereas, studies that found associations between meloxicam treatment and daily milk production increases evaluated production over a far longer period of time.…”
Section: Discussionsupporting
confidence: 86%
“…However, these trials used tablets that required manipulation prior to administration and thus, a more convenient dosage form may improve practicality for dairy producers. Meloxicam oral suspension (MOS, Alberta Veterinary Laboratories Ltd., Alberta, Canada) is a commercially available suspension that has shown efficacy in treating musculoskeletal pain in cattle [15] and preventing pain and inflammation following band castration [9]. Thus, MOS could represent an alternative to the administration of NSAID tablets at parturition.…”
Section: Introductionmentioning
confidence: 99%
“…Meloxicam, a non-steroidal anti-inflammatory drug (NSAID) is a potent, selective cyclooxygenase-2 inhibitor with antipyretic, anti-inflammatory, and analgesic properties [8]. Meloxicam has been used to treat the pain and inflammation associated with a variety of medical conditions and procedures in cattle, including mastitis [9], dehorning [10], castration [11], abdominal surgery [12], and lameness [13]. In calves with mild to moderate diarrhea, researchers found that treating with a single dose of meloxicam parenterally resulted in improved feed and water intakes, higher average daily gains in bodyweight pre-weaning, and earlier weaning ages relative to untreated controls [14].…”
Section: Introductionmentioning
confidence: 99%
“…For cattle, meloxicam has become an intensively investigated extra label drug use NSAID. As described in previous studies, meloxicam offers beneficial effects such as prevention of disease during surgical procedures ( Coetzee et al, 2012a ) and reduction of pain in common procedures of bovine production medicine ( Nagel et al, 2016 ; Coetzee et al, 2012b ). Meloxicam is a member of the oxicam drug class and preferentially inhibits cyclooxygenase II activity, which has a physiologic role in prostaglandin production ( Plumb, 2015 ).…”
Section: Discussionmentioning
confidence: 96%