The uncontrolled use of antibacterial drugs resulted in a wide spread of forms of microorganisms resistant to them. The resistance of most bacteria to one degree or another is observed in relation to almost all existing antibiotics, which led to a significant decrease in the effectiveness of their use not only in veterinary medicine but also in medicine. Therefore, an important task which veterinary service faces is the use of alternative antibacterial drugs. Thus, the development and use of prebiotics in the food of poultry for complete or partial replacement of antibiotics is considered as a new direction of modern scientific research. The authors were the first who studied the effect of the heteropolysaccharides “raspol” and “vetelac” on the organism of broiler chickens. A high pharmacological effect of both drugs was established with a clear advantage of raspol, the use of which, against the background of the absence of antibiotics, had a positive effect on the growth and viability of poultry and caused an increase in the natural resistance of organisms. Thus, prebiotic raspol can be used as an alternative to antibacterial agents in broiler poultry farming. This drug is recommended for the give to broiler chickens with water at the rate of 0.6 g / kg of body weight starting from 7 days of age for 10 days.