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ФГБОУ ВО «Казанская государственная академия ветеринарной медицины имени Н.Э. Баумана» (ФГБОУ ВО Казанская ГАВМ) FSBEI HE «Kazan Bauman State Academy of Veterinary Medicine»(FSBEI HE KSAVM) Печатается по решению редакционной коллегии Казанской государственной академии ветеринарной медицины им. Н.Э. Баумана от 15 Сентября 2018 г

Breeding animals without the use of antibacterial drugs is a relevant branch of modern science, because the entry of national agricultural products into the foreign market provides for the antibacterial drugs absence in raw materials of animal origin. Therefore, in order to improve livability and productivity of animals, it is necessary to constantly monitor the resistance of their bodies, use antibacterial drugs more carefully and eliminate unnecessary or ineffective drugs completely. Thus, an important task facing the veterinary service of the Russian Federation is the complete elimination or reduction of the antibiotics use in animal breeding and the use of drugs that can replace antibacterial ones. We first studied the effect of heteropolysaccharides “raspol” and “gemiv” on broiler bodies. It is established that the used drugs allow eliminating the antibacterial drugs from the broiler ration. In the period of antibacterial drugs exclusion from the broiler preventive treatment scheme these prebiotics cause an increase in poultry gain, increase its livability and natural resistance, while the use of antibiotics in broiler control group negatively affects the body. Recommendations for the use of prebiotics raspol and gemiv in broilers, as an alternative to antibacterial drugs, are provided.

ФГБОУ ВО «Казанская государственная академия ветеринарной медицины имени Н.Э. Баумана» (ФГБОУ ВО Казанская ГАВМ) FSBEI HE «Kazan Bauman State Academy of Veterinary Medicine»(FSBEI HE KSAVM) Печатается по решению редакционной коллегии Казанской государственной академии ветеринарной медицины им. Н.Э. Баумана от 15 Сентября 2018 г

Ðåçþìå. Ðàñïðîñòðàíåíèå àíòèìèêðîáíîé ðåçèñòåíòíîñòè ÿâëÿåòñÿ îäíîé èç ñàìûõ îñòðûõ ïðîáëåì ñîâðåìåííîñòè, íåñóùåé áèîëîãè÷åñêèå è ýêîíîìè÷åñêèå óãðîçû äëÿ âñåõ ñòðàí, ïîýòîìó âûðàùèâàíèå ñåëüñêîõîçÿéñòâåííûõ aeèâîòíûõ áåç ïðèìåíåíèÿ àíòèáèîòèêîâ ÿâëÿåòñÿ àêòóàëüíûì íàïðàâëåíèåì ñîâðåìåííîé íàóêè. Âïåðâûå áûëî èçó-÷åíî äåéñòâèå öèêëîôåðîíà è ãåìèâà íà îðãàíèçì öûïëÿòáðîéëåðîâ. Óñòàíîâëåíî, ÷òî äàííûå èììóíîñòèìóëÿòîðû óâåëè÷èâàþò ïðèðîñòû è ñîõðàííîñòü ïòèöû, ïîâûøàþò åñòåñòâåííóþ ðåçèñòåíòíîñòü îðãàíèçìà.Ïðèìåíåíèå öèêëîôåðîíà ïðè îòñóòñòâèè àíòèáèîòèêîâ â ðàöèîíàõ öûïëÿò-áðîéëåðîâ âûçûâàåò ïîâûøåíèå ïðèðîñòîâ ïòèöû è óâåëè÷èâàåò å¸ ñîõðàííîñòü è åñòåñòâåííóþ ðåçèñòåíòíîñòü, â òî âðåìÿ êàê ïðèñóòñòâèå àíòèáèîòèêîâ îòðèöàòåëüíî âëèÿåò íà îðãàíèçì.Îïòèìàëüíîéäîçîé öèêëîôåðîíà äëÿ öûïëÿò-áðîéëåðîâ ñëåäóåò ñ÷èòàòü 0,003 ìã /êã ìàññû òåëàñ ó÷¸òîì ïîëíîãî èñêëþ÷åíèÿ àíòèáèîòèêîâ èç ðàöèîíà ïòèöû. Ïðèìåíåíèå öûïëÿòàì ãåìèâà èç ðàñ÷¸òà 0,4 ã/êã ìàññû òåëà òàêaeå îêàçûâàåò ðîñòîñòèìóëèðóþùèé ýôôåêò è ïîâûøàåò ôàãîöèòàðíóþ àêòèâíîñòü ïñåâäîýîçèíîôèëîâ è áàêòåðèöèäíóþ àêòèâíîñòü ñûâîðîòêè êðîâè. Äàíûðåêîìåíäàöèè ïî èñïîëüçîâàíèþ öèêëîôåðîíà â ðàöèîíàõ öûïëÿò-áðîéëåðîâ ïðè ïîëíîì îòêàçå îò àíòèáèîòèêîâ. Summary. The spread of antimicrobial resistance is one of the most acute problems of our time, which carries biological and economic threats for all countries, therefore the cultivation of farm animals without the use of antibiotics is an actual direction of modern science. Was first studied the effect of cycloferon and gemiv on the body of broiler chickens. It was found that these Immunostimulants increase the growth and preservation of poultry, increase the natural resistance of the body. The use of cycloferon in the absence of antibiotics in the diets of broiler chickens causes an increase in the growth of poultry and increases its safety and natural resistance, while the presence of antibiotics adversely affects the body. The optimal Ãîðáà÷ À.À.