1933
DOI: 10.1056/nejm193311302092202
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The Use of Sodium Dehydrocholate as a Clinical Test of the Velocity of Blood Flow

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Cited by 26 publications
(8 citation statements)
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“…Early observations as well as more recent studies have demonstrated a relationship between prolongation of various indices of circulation time and LV enlargement, LV dysfunction, reduced cardiac output, and congestive heart failure. [7][8][9][10][11][12][13][14][15][16][17] To our knowledge, this is the first study to explore the hemodynamic significance of LA circulation transit time. The measurement of LATT by CMR is derived from the ratio of volume to flow, based on the principles of indicator dilution theory.…”
Section: Discussionmentioning
confidence: 99%
“…Early observations as well as more recent studies have demonstrated a relationship between prolongation of various indices of circulation time and LV enlargement, LV dysfunction, reduced cardiac output, and congestive heart failure. [7][8][9][10][11][12][13][14][15][16][17] To our knowledge, this is the first study to explore the hemodynamic significance of LA circulation transit time. The measurement of LATT by CMR is derived from the ratio of volume to flow, based on the principles of indicator dilution theory.…”
Section: Discussionmentioning
confidence: 99%
“…A decrease in the pulmonary, arm to arm, and arm to tongue circulation times (22,25,34,36) and histamine reaction time (35) has been reported in non-pregnant cases of hyperthyroidism. It has also been reported that the basal metabolic rate is increased in pregnancy (15,52,53,54).…”
Section: Resultsmentioning
confidence: 95%
“…Anemia in non-pregnant individuals has been reported to cause a decrease in the pulmonary, arm to arm, and arm to tongue circulation times (22,30,34) and histamine reaction time (35).…”
Section: Resultsmentioning
confidence: 99%
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“…
The relationship between metabolism and the velocity of blood flow in thyroid disease has been studied by numerous investigators (1,2,3,4,5,6,7), all of whom have demonstrated that the velocity of blood flow is increased in hyperthyroidism and decreased in myxedema. In addition, the circulation time or the velocity of blood flow was found to be increased in anemia and decreased in congestive heart failure, while in hypertension, no variation from the normal circulation rate was found.

One purpose of this study was to determine if there existed a change in circulation rate in conditions in which the metabolic rate was abnormal, but in which there appeared no evidence of abnormal thyroid function.

…”
mentioning
confidence: 99%