The Use of Synthetic Polymers (Superdisintegrants) in Technology Tablets Containing Ethanol Dry Extract from Asparagus officinalis

Linka, Wojciech Andrzej; Wojtaszek, Ilona; Zgoda, Marian Mikołaj; Kołodziejczyk, Michał Krzysztof

doi:10.17219/pim/61167

Cited by 4 publications

(3 citation statements)

References 9 publications

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“…Analysis of the properties of powder mixtures and reference tablets was carried out in accordance with the recommendations of the Polish Pharmacopoeia X (8,9). Their quality was assessed using the volumeter JEL STAV II (J.Engelsmann AG, Germany), moisture analyzer WS 30 ( Radwag, Poland), tablet hardness tester MT 50 (Pharmatron, Switzerland) and friabilator (ZDM, Polfa, Poland).…”

Section: Methodsmentioning

confidence: 99%

Impact of Excipients on Pharmaceutical Availability of Folic Acid From Tablets

Ostróżka-Cieślik¹,

Dolińska²,

Ryszka³

2018

Acta Poloniae Pharmaceutica - Drug Research

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The impact of excipients contained in individual formulations on the pharmaceutical availability of folic acid was investigated. The release rate of the active substance and the disintegration time of the tablets were analyzed. It has been found that in the presence of sorbitol, glucose and starch, 100% of folic acid is released within 60 min, and in the presence of lactose and starch ñ 95%, and the release rates for them are 0.0717 min-1 and 0.0555 min-1 respectively.

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Section: Methodsmentioning

confidence: 99%

Impact of Excipients on Pharmaceutical Availability of Folic Acid From Tablets

Ostróżka-Cieślik¹,

Dolińska²,

Ryszka³

2018

Acta Poloniae Pharmaceutica - Drug Research

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“…구강 양치액에 요구되는 치료는 치면세균막 축적의 방지, 염증의 감소가 있으며 필요 요건으로는 구강조직에 침투되어야 하고 가능한 오랜 기간 동안 구강 내에서 효과적인 농도가 유지되어야 한다는 것이 다 27) .…”

Section: 고 안unclassified

Effect of a mouthwash containing cetylpyridinium chloride and zinc acetate

Mun

Choi

Kim

et al. 2023

J Korean Acad Oral Health

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Objectives: This study investigated the effects of mouthwashes containing cetylpyridinium chloride and zinc acetate on oral health. Methods: A total of 60 participants were included in the study. Fifty-three participants (27 and 26 participants in the experimental and control groups, respectively) were retained, excluding seven candidates who dropped out. The mouthwash used for the study was spat out after 10-15 ml of mouth-washing for 3 s in the oral cavity after breakfast, lunch, and dinner. Oral examination indices included the gingival (gingival index, PMA index), the patient hygiene performance (PHP index, Turesky plaque index), and the bad breath (BB checker, Oral chroma) indices. Five measurements were taken after 2, 4, 6, 8, and 12 weeks and compared. Results: Measurements of the gingival index showed a statistically significant difference between the experimental and the control groups after 4 weeks, and the PMA index from eight weeks (P<0.05). Measurements of the PHP and Turesky plaque indices showed a significant difference in the experimental and control groups after 4 weeks (P<0.05). Compared to the PHP index before the experiment, that of the experimental group showed a significant index decrease after 2 weeks (P<0.05). Results of measuring bad breath through a BB checker showed a statistically significant difference between the experimental and control groups after 4 weeks (P<0.05). Conclusions: Oral mouthwash products containing cetylpyridinium chloride and zinc acetate relieves gingivitis, removes bacterial plaque, and reduces bad breath.

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“…True density was calculated using the following Eqn., D t = 4mt/πhd 2 , where D t is true density (g/cm 3 ), mt is an average mass of tablet (g), h is an average thickness of tablet (cm) d is an average diameter of tablet (cm) [23] .…”

Section: Water Absorption Index and Wetting Timementioning

confidence: 99%

Effect of API on Powder Flowability, Direct Compression and Properties of Orally Disintegrating Tablets: A Preformulation Study

Nachajski¹,

Bazela²,

Zarzycka³

et al. 2019

pharmaceutical-sciences

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Nachajski et al.: Role of API in the Process of Direct Compression The aim of the study was to analyse the effect of the active pharmaceutical ingredient on the fl owability of the powder and properties of tablets prepared using direct compression method. Each analysed formulation contained one model active pharmaceutical ingredient, diphenhydramine, ketoprofen or loratadine. Granulometric properties of the powder formulations were determined based on bulk density prior and after compression, Hausner ratio, Carr index and angle of repose values. The analysis of manufactured tablets included determination of their hardness, thickness, mass, disintegration time, wettability, contact angle and swelling index values. The preformulation study confi rmed that characteristics of the active pharmaceutical ingredient might have modifi ed physicochemical properties of both powder formulations and tablets.

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The Use of Synthetic Polymers (Superdisintegrants) in Technology Tablets Containing Ethanol Dry Extract from Asparagus officinalis

Cited by 4 publications

References 9 publications

Impact of Excipients on Pharmaceutical Availability of Folic Acid From Tablets

Impact of Excipients on Pharmaceutical Availability of Folic Acid From Tablets

Effect of a mouthwash containing cetylpyridinium chloride and zinc acetate

Effect of API on Powder Flowability, Direct Compression and Properties of Orally Disintegrating Tablets: A Preformulation Study

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