The usefulness of antioxidative enzymes for the estimationof synthetic effects of PGE1 analogue

Pawłowska-Góral, Katarzyna; Wardas, Maria; Maciejewska-Paszek, Izabela; Skiba, Mariusz; Nogaj, Szymon

doi:10.1078/0940-2993-00180

Experimental and Toxicologic Pathology

2001

DOI: 10.1078/0940-2993-00180

|View full text |Cite

The usefulness of antioxidative enzymes for the estimationof synthetic effects of PGE1 analogue

Katarzyna Pawłowska-Góral

Maria Wardas

Izabela Maciejewska-Paszek

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2003

2008

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, prostaglandin E 1 analogue misoprostol (MP) is used as a hepatoprotector in patients with hepatobiliary diseases [4,6].Here we studied hepatoprotective and choleretic activity of MP analogue 2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol (11-deoxymisoprostol, 11-DMP), which was synthesized at the Laboratory of Low-Molecular-Weight Bioregulators (Institute of Organic Chemistry, Ufa Research Center of the Russian Academy of Sciences). Toxicity of 11-DMP is 2-fold lower than that of MP.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Choleretic activity of 2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol on the model of CCl4-induced hepatitis

et al. 2008

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

“…For example, prostaglandin E 1 analogue misoprostol (MP) is used as a hepatoprotector in patients with hepatobiliary diseases [4,6].…”

mentioning

confidence: 99%

Choleretic activity of 2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol on the model of CCl4-induced hepatitis

et al. 2008

View full text Add to dashboard Cite

show abstract

Hepatoprotective action of PGE1 analogue estimated by measuring the concentrations of acetoacetate and β-hydroxybutyrate

Skiba¹,

Maciejewska-Paszek

Pawłowska-Góral

et al. 2003

Experimental and Toxicologic Pathology

View full text Add to dashboard Cite

Protective effects of vitamin E against CCl4-induced hepatotoxicity in rabbits

Pawłowska-Góral

Wardas

et al. 2007

Chemical Papers

View full text Add to dashboard Cite

The influence of CCl4 on the activity of superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GR), the value of the total antioxidant status (TAS), and the concentration of malonic dialdehyde (MDA) and glutathione (GSH) was monitored in plasma or whole blood of rabbits. The administration of CCl4 caused the increase of the SOD activity to approximately 150 % and the decrease in the activity of GPx and GR by about 50 %. These changes were accompanied with the increase in TAS value and MDA concentration and the decrease of GSH concentration. The effect of CCl4 was suppressed by the previous 7 days lasting or simultaneous administration of vitamin E. Oxidative stress caused by CCl4 was accompanied by the development of reactive oxygen forms, especially superoxide radical anion.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

The usefulness of antioxidative enzymes for the estimationof synthetic effects of PGE1 analogue

Cited by 3 publications

References 12 publications

Choleretic activity of 2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol on the model of CCl4-induced hepatitis

Choleretic activity of 2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol on the model of CCl4-induced hepatitis

Hepatoprotective action of PGE1 analogue estimated by measuring the concentrations of acetoacetate and β-hydroxybutyrate

Protective effects of vitamin E against CCl4-induced hepatotoxicity in rabbits

Contact Info

Product

Resources

About