“…[5][6][7][8][9][10] In fact, surgical disciplines have lagged far behind other specialties, such as interventional cardiology, 11 critical care, 12,13 and anesthesia, 14,15 but recently, several surgical fields have reported success with these initiatives, including transplantation, 16,17 orthopedic surgery, [18][19][20] otolaryngology, 21,22 hepatobiliary surgery, 23,24 and trauma. 25 We hypothesized that implementation of a Six Sigma program in perforator flap breast reconstruction could improve operational, financial, and clinical outcomes, by reducing variation, improving quality and efficiency, and optimizing throughput.…”