The usefulness of Mohs’ paste for the treatment of a malignant wound caused by a giant intra-abdominal desmoid tumor

Yamano, Tomoki; Kobayashi, Masayoshi; Yoshimura, Mie; Tsukamoto, Kiyoshi; Noda, Masafumi; Matsubara, Nagahide; Nagita, Akira; Tomita, Naohiro

doi:10.1007/s13691-015-0214-x

Cited by 3 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Esta falta de consenso representa um grande problema na utilização desta substância para fins terapêuticos, uma vez que não oferece princípios básicos de segurança, representando riscos à saúde dos pacientes. Este aspecto se torna ainda mais preocupante quando se leva em consideração a alta toxicidade da pasta de Mosh descrita pela literatura 21 .…”

Section: Discussionunclassified

Tratamento Tópico para o Sangramento em Feridas Tumorais: Uma Revisão Integrativa

Martins¹,

Miranda²,

Pereira³

et al. 2021

SaudColetiv (Barueri)

View full text Add to dashboard Cite

Objetivo: realizar uma revisão integrativa da literatura, focada na identificação e avaliação de estudos primários objetivando o controle tópico do sangramento em feridas tumorais. Métodos: foi feita pesquisa bibliográfica no período de dezembro de 2020 a janeiro de 2021 nas bases de dados Scopus, Cinahl, PubMed e Web of Science e usados os descritores wounds and injuries, hemorrhage, neoplasms e nursing e as palavras chaves symptom management, bleeding e therapeutics. Resultados: A amostra final foi composta por 06 estudos. Os delineamentos mais frequentes foram série de casos/relato de caso, com cinco estudos (83,3%), e um estudo de coorte (16,7%). Portanto, cinco estudos (83,3%) apresentaram nível de evidência 6 (fraca) e um (16,7%), nível de evidência 4 (moderada). Conclusão: recomenda-se que estudos posteriores com melhor delineamento metodológico sejam conduzidos a fim de produzir evidências mais concretas.

show abstract

Section: Discussionunclassified

Tratamento Tópico para o Sangramento em Feridas Tumorais: Uma Revisão Integrativa

Martins¹,

Miranda²,

Pereira³

et al. 2021

SaudColetiv (Barueri)

View full text Add to dashboard Cite

show abstract

“…The application time of MP for skin tumor chemosurgery is approximately 6-24 h, 6) whereas that for managing bleeding and reducing exudate fluid is approximately 15-180 min. 7) Examples of using MP in medical settings in Japan have been scattered to improve the QOL of patients receiving palliative care. [6][7][8][9][10][11] MP is usually prepared in hospitals as it is not available commercially.…”

mentioning

confidence: 99%

“…7) Examples of using MP in medical settings in Japan have been scattered to improve the QOL of patients receiving palliative care. [6][7][8][9][10][11] MP is usually prepared in hospitals as it is not available commercially. [12][13][14] Hospital-prepared MP (Original prescription of MP: O-MP) is difficult to apply to affected areas because its physicochemical properties, such as hardness, viscoelasticity, and malleability, dramatically change over time after preparation.…”

mentioning

confidence: 99%

Evaluation of Tumor Tissue Fixation Effects of Formulation Modified Mohs Pastes in Mice and Their Water-Absorbing Properties

Taguchi

Shigeyama

Ogawa

et al. 2018

Biological & Pharmaceutical Bulletin

View full text Add to dashboard Cite

Mohs paste (MP) is a hospital preparation containing zinc hydrochloride and zinc oxide starch. It is a topical medication used to fixate tissues for the removal of inoperable skin tumors and the management of hemorrhage and exudates, and to prevent foul odor resulting from secondary infections. However, it has problems, such as changes in hardness and viscoelasticity with time and liquefaction by exudate. It has been reported that the modified MP with D-sorbitol (S-MP) and the modified MP using the cellulose instead of starch (C-MP) have excellent physicochemical stability and better handling than original MP (O-MP). In this study, the effect of prescription improvement of MP on the pharmacological effect was examined with reference to water absorbing property, and its tumor tissue invasion fixation depth as an indicator. In the S-MP and C-MP, the amounts of water absorption did not differ significantly from those in the O-MP. The hardness of S-MP was decreased and liquefied like O-MP after absorbing water. In contrast, C-MP retained its form even after water absorption. The subcutaneous tumors in mice treated with modified MP formulations were measured for invasion fixation depth at 6 and 24 h after application. And the tissue status was observed using computed tomography. In all MPs, invasion fixation depth increased depending on application time. S-MP and O-MP depths did not differ significantly. The invasion depths of the C-MP significantly increased compared with those in the O-MP. These results suggest that C-MP had a high tissue fixation rate.

show abstract

Dacarbazine/doxorubicin

2015

Reactions Weekly

View full text Add to dashboard Cite

The usefulness of Mohs’ paste for the treatment of a malignant wound caused by a giant intra-abdominal desmoid tumor

Cited by 3 publications

References 12 publications

Tratamento Tópico para o Sangramento em Feridas Tumorais: Uma Revisão Integrativa

Tratamento Tópico para o Sangramento em Feridas Tumorais: Uma Revisão Integrativa

Evaluation of Tumor Tissue Fixation Effects of Formulation Modified Mohs Pastes in Mice and Their Water-Absorbing Properties

Dacarbazine/doxorubicin

Contact Info

Product

Resources

About