The Utility of a National Surveillance Network to Estimate CKD Prevalence and Identify High-Risk Populations in Primary Care

Rao, Maya K.

doi:10.1016/j.ekir.2019.02.002

Cited by 1 publication

(2 citation statements)

References 9 publications

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“…However, no significant conclusions can be drawn regarding CKD prevalence in Iran, because previous studies in variable environments have been performed on participants in the variable age range. Our estimates are relatively higher than similar reports among adults in American and European countries [30,31]. Of note, the mean age of participants in this study was 48 years, and apparently, the mean eGFR in this group would be lower than in younger age ones.…”

Section: Discussioncontrasting

confidence: 77%

“…This study's results showed that hypertension prevalence in CKD patients was 33.4%, and a person with hypertension (having a blood pressure of BP ≥140/90 mmHg or taking antihypertensive drugs) has 1.18 times higher odds of having CKD than a person without hypertension. In some previous cohort studies on diabetic populations, hypertension was an independent predictor of CKD [2,19,[29][30][31]49]. The mechanisms of hypertension in CKD include volume overload, sympathetic overactivity, salt retention, endothelial dysfunction, and alterations in hormonal systems that regulate blood pressure (BP) [47].…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of chronic kidney diseases and its determinants among Iranian adults: results of the first phase of Shahedieh cohort study

et al. 2022

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Background Chronic kidney disease (CKD) is one of the major global causes of mortality, described as the most neglected chronic disease. This study aimed to determine the prevalence and determinants of CKD in the setting of the Shahedieh cohort study in Yazd, Iran. Methods This cross-sectional study was conducted on adults in the baseline phase of the Shahedieh cohort study in Yazd, Iran. In this study, 9781 participants aged 30–73-year-old were investigated. The data used in this study included demographic and clinical variables and blood samples. Adjusted odds ratios were employed using multivariate logistic regression; meanwhile, population attributable risks for CKD were calculated and reported. Results CKD prevalence was 27.5% (95%CI: 26.57–28.34) in all participants, 24% in male, and 30.3% in female. The results of multivariate logistic regression analysis identified age (OR = 1.89, 95%CI:1.082–1.96), women (OR = 1.62, 95%CI: 1.45–1.79), BMI ≥ 30 (OR = 1.40,95%CI: 1.20–1.62), diabetes (OR = 1.38, 95%CI: 1.22–1.57), hypertriglyceridemia(OR = 1.20, 95%CI: 1.01–1.43), history of cardiovascular disease (OR = 1.20, 95%CI: 1.01–1.43), hypertension (OR = 1.18, 95%CI: 1.04–1.33), smoking (OR = 1.17, 95% CI: 1.02–1.33), LDL ≥ 130 (OR = 1.15, 95%CI: 1.01–1.31), history of kidney stone (OR = 1.14, 95%CI: 1.01–1.32) and hypercholesterolemia (OR = 1.14, 95%CI: 1.01–1.32) as risk factors for CKD. Among individual factors, obesity (11.25%), Hypertriglyceridemia (9.21%), LDL ≥ 130 (7.12%) had the greatest Population-Attributable Fraction, followed by Hypercholesterolemia (5.2%), diabetes (5.05%), smoking (3.73%) and high blood pressure (2.82%). Conclusion The results showed that the main determinants of CKD are potentially modifiable risk factors. Therefore, implementing early detection and screening programs in people at risk as well as preventive measures such as lifestyle modification programs and risk factors controlling can prevent the disease.

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Section: Discussioncontrasting

confidence: 77%