The Utility of Bone Scans in Rheumatology

Duncan, Iain; Dorai-Raj, Anna; Khoo, Kenneth; Tymms, Kathleen; Brook, Andrew

doi:10.1097/00003072-199901000-00003

Cited by 9 publications

(3 citation statements)

References 3 publications

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“…For many years, the importance of BS for measuring joint inflammation in RA patients has been emphasized (5, 6). Several previous studies have also confirmed that BS has a high rate of clinical utility in rheumatology (7). Moreover, increased blood pool activity of the involved joints on BS correlated with inflammatory synovitis, which is an early sign of RA (8).…”

Section: Introductionmentioning

confidence: 60%

The Role of Bone Scintigraphy in the Diagnosis of Rheumatoid Arthritis According to the 2010 ACR/EULAR Classification Criteria

et al. 2014

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We aimed to investigate the role of bone scintigraphy (BS) in the diagnosis of rheumatoid arthritis (RA) as a supplement to the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria. A total of 156 patients who underwent BS with screening laboratory to confirm RA were enrolled. We divided them into two groups according to the presence of arthritis upon the first physical examination, and evaluated the diagnostic validity of BS as an independent (BS only) or assistant diagnostic tool using the 2010 criteria (BS-assisted). Seventy-five patients had active arthritis (Group I), while the remaining 81 patients did not (Group II). Among them, 56 patients in group I and 5 patients in group II were finally classified as RA. In the group I patients who were eligible for application of the 2010 criteria, the sensitivity of the BS only and BS-assisted diagnosis was not superior to that of the 2010 criteria. However, BS-assisted diagnosis showed high positive prediction values in group I patients with 2010 criteria score < 6 and group II patients. Therefore, BS is still helpful to detect RA even after the introduction of the 2010 criteria, especially among patients who do not satisfy the 2010 criteria as well as those who are ineligible for the 2010 criteria due to dubitable arthritis at clinical presentation.Graphical Abstract

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Section: Introductionmentioning

confidence: 60%

The Role of Bone Scintigraphy in the Diagnosis of Rheumatoid Arthritis According to the 2010 ACR/EULAR Classification Criteria

et al. 2014

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“…The indications for performing a bone scan specifically in OA are limited, with scintigraphy used in a clinical setting to differentiate between pathologies. Historically, bone scans were requested to confirm or exclude a diagnosis of inflammatory arthritis, malignancy and fractures in one study (Duncan, Dorai-Raj et al 1999). OA was the final diagnosis in 11% of scans.…”

Section: Bone Scansmentioning

confidence: 99%

The Application of Imaging in Osteoarthritis

Hing¹,

Harris²,

Ejindu³

et al. 2012

Principles of Osteoarthritis- Its Definition, Character, Derivation and Modality-Related Recognition

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“…The utility of Tc99m MDP bone scans in the successful elimination of Rheumatoid Arthritis in 87% of cases and fruitful confirmation in 80% cases in a study of 139 bone scans in Rheumatoid Arthritis is reported by Duncan et al [1]. Vos et al has reported the comprehensive utility and role of various scintigraphic techniques in comparison with other radiological imaging methods [2].…”

Section: Introductionmentioning

confidence: 99%

Scintimetric Evaluation of the Rheumatoid Arthritis Involvement by Dr. V. Siva’s Retention Ratio-(Preliminary Report)

Sivasubramaniyan¹,

Venkataramaniah²

2017

J Arthritis

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Aim: This study aims to propose the utility of Scintimetric Characterization of the tracer activity uptake in the joints afflicted by Rheumatoid arthritis in the bone scans. Materials and method:Three out of five patients of confirmed Rheumatoid arthritis who had bone scans for Bone and joint pains showed presence of skeletal hot spots in various joints. They were subjected to the scintimetric evaluation of the skeletal hot spots by Dr. V. Siva's retention ratio by repeating the 24 hr delayed bone scans. The 58 skeletal hotspots seen in various joint spaces were subjected to the calculation of maximum counts in 3 hr and 24 hr bone scans. They were tabulated and 3/24 hr Dr. V. Siva's Retention Ratio was calculated and analysed.Results: They showed a mean of 5.91 ± 0.35 and standard error of means as 0.3496. The estimated variance was 8.8408 and the estimated standard deviation was 2.9734. For this sample size the estimated variance was 6.6306 and estimated standard deviation was 2.575 by HOJO's modification. This was unavoidable due to very small size of the Sample population. Conclusion:Thus this study had shown that the scintimetric evaluation of the skeletal hotspots in the Rheumatoid Arthritis Patients showed a definitive benign value. This could provide a firm base line value to assess the response to treatment and progression as well.

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The Utility of Bone Scans in Rheumatology

Cited by 9 publications

References 3 publications

The Role of Bone Scintigraphy in the Diagnosis of Rheumatoid Arthritis According to the 2010 ACR/EULAR Classification Criteria

The Role of Bone Scintigraphy in the Diagnosis of Rheumatoid Arthritis According to the 2010 ACR/EULAR Classification Criteria

The Application of Imaging in Osteoarthritis

Scintimetric Evaluation of the Rheumatoid Arthritis Involvement by Dr. V. Siva’s Retention Ratio-(Preliminary Report)

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