The utility of EEG in dementia: a clinical perspective

Adamis, Dimitrios; Sahu, Sunita; Treloar, Adrian

doi:10.1002/gps.1393

Cited by 50 publications

(27 citation statements)

References 92 publications

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“…The main EEG application should be the differential diagnosis between dementia and other conditions characterized by peculiar EEG patterns such as Creutzfeldt-Jacob's disease, toxic-metabolic encephalopathy, or other psychiatric condition such as pseudodepressive dementia [90]. In a broader sense EEG can also be used to stage the severity of dementia and provide information for prognostic purposes [91]. Finally, it would be useful in evaluating the biological effect of drugs [72, 92].…”

Section: Discussionmentioning

confidence: 99%

Electroencephalogram and Alzheimer’s Disease: Clinical and Research Approaches

Tsolaki

Kazis

Kompatsiaris

et al. 2014

International Journal of Alzheimer's Disease

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Alzheimer's disease (AD) is a neurodegenerative disorder that is characterized by cognitive deficits, problems in activities of daily living, and behavioral disturbances. Electroencephalogram (EEG) has been demonstrated as a reliable tool in dementia research and diagnosis. The application of EEG in AD has a wide range of interest. EEG contributes to the differential diagnosis and the prognosis of the disease progression. Additionally such recordings can add important information related to the drug effectiveness. This review is prepared to form a knowledge platform for the project entitled “Cognitive Signal Processing Lab,” which is in progress in Information Technology Institute in Thessaloniki. The team tried to focus on the main research fields of AD via EEG and recent published studies.

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Section: Discussionmentioning

confidence: 99%

Electroencephalogram and Alzheimer’s Disease: Clinical and Research Approaches

Tsolaki

Kazis

Kompatsiaris

et al. 2014

International Journal of Alzheimer's Disease

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“…4 Quantitative electroencephalography (Q-EEG) and P300 event-related potential have been studied in various disorders of brain function with cognitive impairment, especially in dementing illnesses and mild cognitive decline. 5 Q-EEG uses computer software to provide topographic analysis of brain activity. In experimental animal studies, Q-EEG has also been used to quantify the early cerebral dysfunction after CA.…”

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confidence: 99%

Cognitive and Neurophysiological Outcome of Cardiac Arrest Survivors Treated With Therapeutic Hypothermia

Tiainen

Poutiainen

Kovala

et al. 2007

Stroke

105

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Background and Purpose-Cognitive deficits are common in survivors of cardiac arrest (CA). The aim of this study was to examine the effect of therapeutic hypothermia after CA on cognitive functioning and neurophysiological outcome. Methods-A cohort of 70 consecutive adult patients resuscitated from out-of-hospital ventricular fibrillation CA were randomly assigned to therapeutic hypothermia of 33°C for 24 hours accomplished by external cooling or normothermia.Neuropsychological examination was performed to 45 of the 47 conscious survivors of CA (27 in hypothermia and 18 in normothermia group) 3 months after the incident. Quantitative electroencephalography (Q-EEG) and auditory P300 event-related potentials were studied on 42 patients at the same time point. Results-There were no differences between the 2 treatment groups in demographic variables, depression, or delays related to the resuscitation. No differences were found in any of the cognitive functions between the 2 groups. 67% of patients in hypothermia and 44% patients in normothermia group were cognitively intact or had only very mild impairment.Severe cognitive deficits were found in 15% and 28% of patients, respectively. All Q-EEG parameters were better in the hypothermia-treated group, but the differences did not reach statistical significance. The amplitude of P300 potential was significantly higher in hypothermia-reated group. Conclusions-The use of therapeutic hypothermia was not associated with cognitive decline or neurophysiological deficits after out-of-hospital CA.

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“…We are not aware of any data that support this contention and are unsure why this patient was diagnosed with underlying alcohol-related, dietary-related, cerebro-vascular psychopathology rather than intractable, partially responsive chronic HE. The electroencephalogram (EEG) was grossly abnormal and although slowing of the mean cycle frequency may be observed in people with dementia, this degree of EEG abnormality if attributable to dementia per se, would be accompanied by a far greater degree of clinical abnormality than just 'inappropriateness' [2]. Finally, as neuropsychiatric comorbidities and age effects may compromise the ´personal best performance´, utilization of this information and, in the absence of normative reference data, its translation into guidelines useful for health systems and legislators would present considerable difficulties.…”

Section: To the Editormentioning

confidence: 99%