The Vascular Arrangement of the Sinus Mucosa: A Study in Rabbits

Abstract

Seventy-seven New Zealand White rabbits, with an average weight of 3 kg, were used in studies on the paranasal sinus. Replica moulds of the sinus revealed a sinus cavity composed of three compartments with a total volume of 2-3 ml. The sinus cavity was connected with the nasal cavity through an ostium. By intravascular injection of silicone rubber for dissection and of methacrylate for production of corrosion casts, the vascular bed and the vessels passing to and from the sinus cavity were studied. The main arterial supply and venous drainage takes place through the ostium, which is surrounded by a dense venous plexus. Compared with the nasal mucosa, the number of vessels per volume unit is about the same in the sinus mucosa. Many vessels perforating through the osseous walls, both arteries and veins, were found, however, indicating that the blood supply is not derived exclusively from vessels coming through the ostium.

Comparative Histomorphometric Analysis of Maxillary Sinus Augmentation With and Without Bone Grafting in Rabbit

“…Rabbits' sinuses have known to be similar to human sinuses. 20 Thus, rabbits were used in this study to verify the mechanism of new bone formation in the sinus, histologically. 20 Faster new bone formation in the experimental group than in the control group was revealed histologically in this study.…”

A Clinical Trial on the Treatment of Chronic Rhinosinusitis with Continuous Ultrasound

“…Poor blood circulation is one of the major factors that contributes to medical failure and chronicity of the disease 17) . A number of physiotherapy methods have been reported to treat sinusitis.…”

Development and characterization of an animal model of dental sinusitis

“…Furthermore, human and rabbit paranasal sinuses are anatomically similar: the maxillary sinus cavity communicates with the nasal cavity through a well-defined ostium, as well as having dental roots in close proximity to the sinus floor. These conditions are suitable for experiments involving sinus physiology and pathophysiology [21,22]]. …”