The vascular status of a heterogeneous group of patients with hypertension, with particular emphasis on renal function

Moyer, John H.; Heider, Charles; Pevey, K; Ford, Ralph V.

doi:10.1016/0002-9343(58)90305-x

Cited by 34 publications

(5 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In patients with hypertension, a progressive reduction of renal blood flow and glomerular filtration rate with an increase in blood pressure as well as an increase in complications is observed by M oyer et a i [17]. The results in this study are generally in agreement with this observation.…”

Section: Discussionsupporting

confidence: 91%

Intrarenal Blood Flow in Essential Hypertension

Nomura¹,

Kurosaki²,

Inasaka³

et al. 1974

Nephron

View full text Add to dashboard Cite

Intrarenal blood flow was measured by the ¹³³Xe washout method in 22 patients with essential hypertension. Mean RBF, the percentage of flow in component I, and fraction of renal mass supplied by component I were significantly reduced in patients with proteinuria, severe nephrosclerosis, cardiomegaly, and retinal changes of Keith-Wagener III and IV. Flow rate in component I was also reduced in the patients with severe nephrosclerosis, retinal changes of Keith-Wagener III and IV, and proteinuria. We conclude that redistribution of intrarenal blood flow occurs in essential hypertension with renal, cardiac, and retinal complications.

show abstract

Section: Discussionsupporting

confidence: 91%

Intrarenal Blood Flow in Essential Hypertension

Nomura¹,

Kurosaki²,

Inasaka³

et al. 1974

Nephron

View full text Add to dashboard Cite

show abstract

“…In all, refusals accounted for 9 per cent of the contacts but only 1.1 per cent of the contacts gave illness as a reason and were not seen in the hospital or at home. 2 The hypertensive group represents all subjects between the ages of 30 and 69 years seen in a 1-year period whose blood pressure on all determinations was greater than 140 mm. Hg systolic, 90 nuni.…”

Section: Methodsmentioning

confidence: 99%

Hypertension and Ischemic Heart Disease in Hiroshima, Japan

Switzer

1963

Circulation

View full text Add to dashboard Cite

A random sampling of Hiroshima residents, comprising 1,051 males and 1,872 females, has been studied with respect to the interrelations of hypertension, ischemic heart disease, blood lipid levels, and ionizing irradiation experienced during the atom bombing of 1945. No significant effect of ionizing irradiation upon the cardiovascular system has been detected. No major difference in age-sex specific mean blood pressures between Hiroshima residents and a suitable white American comparison group was found. Dissimilarities noted with other groups compared are considered due to the sum of sampling bias, varying technics, and coincidental environmental factors rather than a true racial difference. Blood pressure levels, stable from puberty through young adulthood, begin to rise early in middle age and continue to rise into old age. As a result, hypertension as clinically defined (140/90), is common in middle-aged and elderly Japanese. In 94.4 per cent of instances, or more, a demonstrable etiology for hypertension could not be found; these are considered to represent essential hypertension. An accelerated course with fulminating vascular deterioration was suspected in only 1 per cent of the hypertensive subjects. As a result, advanced retinopathy and renal failure were rarely seen. Electrocardiographic evidence of left ventricular hypertrophy occurred in 7.2 per cent of the hypertensive Japanese in this study, and was readily correlated with the ambient systolic blood pressure. Evidence of ischemic heart disease and congestive failure is rare and distinctly less common than in American males unselected as to blood pressure levels. In contrast, mortality statistics indicate cerebrovascular disease to be at least as common in Japan as in the U. S. Japanese exhibit low serum cholesterol concentrations by Western standards and elevated levels are predominantly limited to the obese. Both factors appear of importance in the occasional hypertensive Japanese with ischemic heart disease. The therapeutic implication of this observation is briefly discussed.

show abstract

“…Der Unterschied dieser beiden Gruppen ist bei unbehandelter maligner Hypertonie noch deutlicher (9,14,42 Die Todesursachen erfolgreich behandelter maligner Hypertoniker erfahren gegenüber unbehandelten insofern eine Modifikation (11,13,15,23,24,34,36,37,46), als der Anteil der Urämie und der Herzinsuffizienzen zugunsten der arterioskierotischen Komplikationen (zerebrovaskuläre Insulte, Koronarverschlüsse) und die Enzephalorrhagien zugunsten der Enzephalomalazien abnehmen. In unserem Kranken-gut kommt diese Verschiebung der Todesursachen allerdings weniger zum Ausdruck, möglicherweise wegen des relativ hohen Anteils an unbekannten oder unsicheren Todesursachen.…”

Section: Prognose Bei Komplikationenunclassified