The Vertex View in Routine Brain Scanning

Holmes, Richard A.; North, Wendy A.

doi:10.2214/ajr.106.2.347

Cited by 6 publications

(3 citation statements)

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“…In one study it was found to be positive in 90% of proven tumors (Holmes, 1969). Another worker found it to be positive when the other four views were negative (Overton et al, 1965~).…”

Section: Vertexmentioning

confidence: 97%

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The use of the brain scan in the diagnosis of intracranial neoplasia

Handmaker

Schall

1971

Journal of Surgical Oncology

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The brain scan has become a safe, efficient, and accurate method of screening patients who are suspected of having intracranial abnormalities. Tumor detection and localization are now possible in approximately 90% of patients seen, comparing favorably with results of angiography and pneumoencephalography. Improvements in radionuclides and detection equipment have made possible refinements of techniques to allow study of cerebral vasculature a t the time of nuclide injection for the routine static studies. Certain tumors have been found to have specific characteristics on the dynamic and static brain scans and can be predicted with some certainty in many instances. Normal scan anatomy and the various histologic tumor types and their patterns are described.

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“…In one study it was found to be positive in 90% of proven tumors (Holmes, 1969). Another worker found it to be positive when the other four views were negative (Overton et al, 1965~).…”

Section: Vertexmentioning

confidence: 97%

“…While not considered a 'routine' view in many institutions, the vertex view may yield the highest percentage of visualized tumors. In one study it was found to be positive in 90% of proven tumors (Holmes, 1969). Another worker found it to be positive when the other four views were negative (Overton et al, 1965~).…”

Section: Vertexmentioning

confidence: 97%

The use of the brain scan in the diagnosis of intracranial neoplasia

Handmaker

Schall

1971

Journal of Surgical Oncology

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“…Historically, in planar scintigraphy the use of vertex views (i.e., imaging with the detector facing the top of the patient's head) was found to be useful for locating lesions in the brain (Overton et al 1965, Holmes & North 1969, Holmes 1971. However, while the advantages of incorporating the vertex view were noted, activity arising from organs and tissues inferior to the brain were problematic.…”

Section: Introductionmentioning

confidence: 99%

Inclusion of quasi-vertex views in a brain-dedicated multi-pinhole SPECT system for improved imaging performance

et al. 2021

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With brain-dedicated multi-detector systems employing pinhole apertures the usage of detectors facing the top of the patient’s head (i.e. quasi-vertex (QV) views) can provide the advantage of additional viewing from close to the brain for improved detector coverage. In this paper, we report the results of simulation and reconstruction studies to investigate the impact of the QV views on the imaging performance of AdaptiSPECT-C, a brain-dedicated stationary SPECT system under development. In this design, both primary and scatter photons from regions located inferior to the brain can contribute to SPECT projections acquired by the QV views, and thus degrade AdaptiSPECT-C imaging performance. In this work, we determined the proportion, origin, and nature (i.e. primary, scatter, and multiple-scatter) of counts emitted from structures within the head and throughout the body contributing to projections from the different AdaptiSPECT-C detector rings, as well as from a true vertex view detector. We simulated phantoms used to assess different aspects of image quality (i.e. uniform activity concentration sphere, and Derenzo), as well as anthropomorphic phantoms with different count levels emulating clinical 123I activity distributions (i.e. DaTscan and perfusion). We determined that attenuation and scatter in the patient’s body greatly diminish the probability of the photons emitted outside the volume of interest reaching to detectors and being recorded within the 15% photopeak energy window. In addition, we demonstrated that the inclusion of the residual of such counts in the system acquisition does not degrade visual interpretation or quantitative analysis. The addition of the QV detectors improves volumetric sensitivity, angular sampling, and spatial resolution leading to significant enhancement in image quality, especially in the striato-thalamic and superior regions of the brain. Besides, the use of QV detectors improves the recovery of clinically relevant metrics such as the striatal binding ratio and mean activity in selected cerebral structures. Our findings proving the usefulness of the QV ring for brain imaging with 123I agents can be generalized to other commonly used SPECT imaging agents labelled with isotopes, such as 99mTc and likely 111In.

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Hirnszintigraphie

Zeidler¹

1978

Nuklearmedizin / Nuclear Medicine

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The Vertex View in Routine Brain Scanning

Cited by 6 publications

References 1 publication

The use of the brain scan in the diagnosis of intracranial neoplasia

The use of the brain scan in the diagnosis of intracranial neoplasia

Inclusion of quasi-vertex views in a brain-dedicated multi-pinhole SPECT system for improved imaging performance

Hirnszintigraphie

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