The volume of trapped gas in healthy children aged 7–16

Svenonius, E.; Kautto, R.

doi:10.1007/bf02713993

Cited by 10 publications

(10 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chest X-rays were scored according to Brasfield's (12). Most data are presented as percentage of the predicted value according to the actual height (11,13,14).…”

Section: Methodsmentioning

confidence: 99%

Long‐term Effects of Physical Exercise on Working Capacity and Pulmonary Function in Cystic Fibrosis

et al. 1987

View full text Add to dashboard Cite

Seven patients with cystic fibrosis aged 6 to 20 were enrolled for 30 months in a daily exercise program. After 12 months conventional chest physiotherapy was withdrawn. Patients with low initial Shwachman scores improved as regards maximal working capacity. Spirometric data and volume of trapped gas indicated opening of closed airways. We suggest that physical exercise in general should be the basis of pulmonary therapy in cystic fibrosis. Other forms of physiotherapy are advisable when hard physical exercise is not feasible.

show abstract

“…Chest X-rays were scored according to Brasfield's (12). Most data are presented as percentage of the predicted value according to the actual height (11,13,14).…”

Section: Methodsmentioning

confidence: 99%

Long‐term Effects of Physical Exercise on Working Capacity and Pulmonary Function in Cystic Fibrosis

et al. 1987

View full text Add to dashboard Cite

show abstract

“…The discrepancies seen in earlier N 2 MBW infant [48], paediatric [19, 37,103,104,105] and adult [45, 104] studies may relate to external equipment dead-space and whether dead space was adequately corrected for in subsequent calculations. It also highlights the need for more current N 2 MBW normative data.…”

Section: Current and Future Roles In The Clinic And In Researchmentioning

confidence: 99%

Inert Gas Washout: Theoretical Background and Clinical Utility in Respiratory Disease

Robinson

Goldman²,

Gustafsson³

2009

Respiration

213

211

View full text Add to dashboard Cite

Inert gas washout was first described more than 60 years ago and 2 principal tests have been developed from it: the single breath and multiple breath washout (MBW) techniques. The invention of fast responding gas analysers almost 60 years ago and small computers 30 years later have facilitated breath-by-breath analysis and the development of sophisticated analysis techniques. It is now possible to detect not only the degree of pulmonary ventilation inhomogeneity, but also to gain important insight into the location of the underlying disease process. While single breath washout requires a full vital capacity effort, tidal breathing during the multiple breath test requires minimal co-operation and co-ordination, and is feasible in subjects of all ages. Available MBW normative data from parameters, such as the lung clearance index, appears to vary minimally with age, making MBW particularly useful to follow children longitudinally. Multiple breath inert gas washout has demonstrated improved sensitivity, in comparison to spirometry, in the early detection of a number of important disease processes, including cystic fibrosis. Despite this, these important techniques remain under-utilised in the clinical setting and there is a lack of commercially available devices currently available. The recent resurgence of research in this area has produced a large number of important studies and a pronounced international interest has developed in these techniques. This review article will provide an overview of the theoretical background of inert gas washout and analysis indices, review important physiological and clinical insights gained from research to date (as well as from our own experience) to illustrate its utility, and outline the challenges that lie ahead in incorporating these techniques into the mainstream clinical setting.

show abstract

“…The children then inhaled 200 Jig salbutamol from a dose aerosol and 10 min later a new lung function examination was performed. The VTG values were significantly smaller (more normal) than VTG values from healthy children (12 During the pollen-free season the VTG values were statistically somewhat better (lower) (P < 0.01) than in healthy children of the same age. The 10 healthy children had been examined in the same manner.…”

Section: Methodsmentioning

confidence: 67%

“…Although both values were within the normal range, the increase was significant (> 3 errors of a single determination (12)). She had also a significantly high VTG and VTG/TLC% (> +2 SD) and her Ng wash-out showed uneven gas distribution.…”

Section: Wovmentioning

confidence: 74%

“…VTG in per cent of VC (VTG/VC%) and VTG in per cent of total lung capacity (VTG/TLC%) were also calculated. Table 1 presents lung function data of the children during their pollen-free and pollen seasons in per cent of predicted normal (12) and the change between the two times for examination. The children then inhaled 200 Jig salbutamol from a dose aerosol and 10 min later a new lung function examination was performed.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Lung Function Studies in Children with Allergic Rhinitis

Svenonius

Arborelius

Kautto

et al. 1982

Allergy

Self Cite

View full text Add to dashboard Cite

Thirty carefully selected children with seasonal allergic rhinitis but without history or signs of lung involvement were examined clinically and by lung function tests during the pollen season as well as in the pollen-free season. During the pollen-free season the children had - if anything - slightly better lung function than a healthy control material. During the pollen season the only change was a slight increase in FRC and a decrease in lung clearance index, directly proportional to the change in FRC. Sixteen of the children performed an exercise test in the pollen-free season. A small increase in the volume of trapped gas (VTG) was noted, indicating a subclinical spasm in small airways. Salbutamol inhalation after exercise reduced VTG below base-line values, indicating disappearance of subclinical bronchospasm. Hay fever children thus have a tendency towards bronchospasm after, exercise in the pollen-free season, which, however, is of no clinical importance, as their VTG also after the exercise was less (better) than the predicted normal.

show abstract

The volume of trapped gas in healthy children aged 7–16

Cited by 10 publications

References 10 publications

Long‐term Effects of Physical Exercise on Working Capacity and Pulmonary Function in Cystic Fibrosis

Long‐term Effects of Physical Exercise on Working Capacity and Pulmonary Function in Cystic Fibrosis

Inert Gas Washout: Theoretical Background and Clinical Utility in Respiratory Disease

Lung Function Studies in Children with Allergic Rhinitis

Contact Info

Product

Resources

About