Theoretical comparison of light sources for use in optical coherence tomography

Sainter, Ann; King, Terence A.; Dickinson, Mark

doi:10.1117/12.491307

Cited by 7 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An optical fiber-lensed probe with a diameter as small as 0.5 mm is suitable for OCT imaging, especially for in vivo intravascular imaging. Based on interaction of near infrared light with different human tissues, the range of penetration depth is from 0.5 mm to 3 mm [17]. Working distance range of an ultra-small fiber-based lense [15] can be designed from 0.4 to 1.2 mm for matching the penetration depth of tissues tested.…”

Section: Methodsmentioning

confidence: 99%

Imaging of arterial plaque by quadrature swept-source optical coherence tomography with signal to noise ratio enhancements

Mao¹,

Flueraru²,

Chang³

2011

JBiSE

View full text Add to dashboard Cite

Arterial plaque from a myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbit is visualized and characterized using a signal to noise ratio enhanced swept-source optical coherence tomography system with a quadrature interferometer (QSS-OCT). A semiconductor optical amplifier is used in the sample arm to amplify the weak signal scattered from arterial plague. Signal to noise ratio improvement are demonstrated in our QSS-OCT system. This finding results into an increase of the penetration depth possible in OCT images, from 1 mm to 2 mm. Preliminary results show that vulnerable plaque with fibrous cap, macrophage accumulations and calcification in the arterial tissue are measurable with our QSS-OCT system.

show abstract

Section: Methodsmentioning

confidence: 99%

Imaging of arterial plaque by quadrature swept-source optical coherence tomography with signal to noise ratio enhancements

Mao¹,

Flueraru²,

Chang³

2011

JBiSE

View full text Add to dashboard Cite

show abstract

“…In most biomedical imaging systems, light from the probe will be directed into a turbid tissue. Based on interaction properties of light with turbid tissue [21], the range of penetration depth is from 0.5-3 mm at near infrared wavelengths. For example, the penetration depths are 0.7 mm and 3.0 mm in human skin and liver, respectively, at 1300 nm, a conventional wavelength used in OCT systems.…”

Section: Design Criteriamentioning

confidence: 99%

Fiber lenses for ultra-small probes used in optical coherent tomography

Mao¹,

Chang²,

Flueraru³

2010

JBiSE

View full text Add to dashboard Cite

We present a design, construction and characterization of different variations of GRIN and ball fiber lenses, which were recently proposed for ultra-small biomedical imaging probes. Those fiber lens modules are made of a single mode fiber and a GRIN or ball fiber lens with or without a fiber spacer between them. The lens diameters are smaller than 0.3 mm. We discuss design methods, fabrication techniques, and measuring performance of the fiber lenses. The experimental results are compared to their modeling results. The fabrication of a high quality beam director for both lens types is presented as well. These fiber integrated beam directors could be added on the tips of the fiber lenses for side-view probes. A needle probe made by these fiber lenses is demonstrated as a sample of the ultra-small probe for biomedical imaging application. In vivo human finger images acquired by a swept source optical coherence tomography using the fiber lenses with different beam profiles were shown, which indicates the important impact of fibe

show abstract

“…An optical fiberlensed probe with a diameter as small as 0.5 mm is suitable for OCT imaging, particularly for in vivo intravascular imaging. Based on the interaction of near-infrared light with different human tissues, the penetration depth ranges from 0.5 to 3 mm [20]. The working distance range of an ultrasmall fiber-based lens [18] can be designed up to 1.2 mm to match the penetration depth into the tissues tested.…”

Section: B Tissues and Probesmentioning

confidence: 99%