The effects of wall suction on the entropy generation rate in a two-dimensional steady film condensation flow on a horizontal tube are investigated theoretically. In analyzing the liquid flow, the effects of both the gravitational force and the viscous force are taken into account. In addition, a film thickness reduction ratio,Sf, is introduced to evaluate the effect of wall suction on the thickness of the condensate layer. The analytical results show that, the entropy generation rate depends on the Jakob number Ja, the Rayleigh number Ra, the Brinkman number Br, the dimensionless temperature differenceψ, and the wall suction parameterSw. In addition, it is shown that in the absence of wall suction, a closed-form correlation for the Nusselt number can be derived. Finally, it is shown that the dimensionless entropy generation due to heat transfer,NT, increases with an increasing suction parameterSw, whereas the dimensionless entropy generation due to liquid film flow friction,NF, decreases.